Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ASPH | Q12797 | 2/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.37 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31032278 | 1.00 | KDM4E (0.41) | KDM4EASPHKDM8GAAMAPK1 | |
| SCHEMBL11894710 | 0.85 | KMO (0.46) | KDM4EASPHKDM8MAPK1L3MBTL1 | |
| SCHEMBL15350397 | 0.83 | KDM4E (0.40) | KDM4EASPHKDM8MAPK1L3MBTL1 | |
| SCHEMBL30546897 | 0.79 | KDM4E (0.45) | KDM4EASPHKDM8MAPK1L3MBTL1 | |
| SCHEMBL15349985 | 0.77 | KMT2A (0.40) | KDM4EASPHKDM8MAPK1L3MBTL1 | |
| SCHEMBL21078949 | 0.76 | MAPT (0.42) | KDM4EASPHKDM8MAPK1L3MBTL1 | |
| SCHEMBL18017222 | 0.75 | UHRF1 (0.42) | GAAALDH1A1 | |
| SCHEMBL15350001 | 0.75 | ASPH (0.46) | KDM4EASPHKDM8L3MBTL1ALDH1A1 | |
| SCHEMBL71437 | 0.75 | PDE4A (0.48) | PDE4AKMO | |
| SCHEMBL7083217 | 0.74 | KDM4E (0.50) | KDM4EASPHKDM8MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |