Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | STK17B | O94768 | 9/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11861138 | 1.00 | RAB9A (0.68) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29537543 | 1.00 | RAB9A (0.68) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10734524 | 0.85 | RAB9A (0.80) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10734520 | 0.85 | RAB9A (0.80) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19462869 | 0.83 | STK17B (0.74) | MAPTMEN1KMT2AACHEKDM4E | |
| SCHEMBL10912003 | 0.83 | STK17B (0.74) | MAPTMEN1KMT2AACHEKDM4E | |
| SCHEMBL19462733 | 0.83 | STK17B (0.89) | MAPTMEN1KMT2AACHEKDM4E | |
| SCHEMBL19499394 | 0.83 | STK17B (0.89) | MAPTMEN1KMT2AACHEKDM4E | |
| SCHEMBL6966601 | 0.82 | STK17B (0.74) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5579527 | 0.81 | RAB9A (1.00) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053933-A1 | THERAPEUTIC AURONES | Middle Tennessee State University (US) | 2021-02-25 | — | — | US | disclosed |
| US-20200399238-A1 | THERAPEUTIC AURONES | Middle Tennessee State University (US) | 2020-12-24 | — | — | US | disclosed |
| WO-2020223439-A1 | AURONES AND METHODS OF USING AURONES TO TREAT TUBERCULOSIS | Middle Tennessee State University (US) | 2020-11-05 | — | — | WO | disclosed |
| US-20190169151-A1 | THERAPEUTIC AURONES | Middle Tennessee State University (US) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399238-A1 | THERAPEUTIC AURONES | AURKA, PIGS, PRF1 | RAB9A 2162/4885MAPT 3325/4885MEN1 2702/4885 |
| US-20210053933-A1 | THERAPEUTIC AURONES | AURKA, PIGS, PRF1 | RAB9A 2162/4885MAPT 3325/4885MEN1 2702/4885 |
| US-20190169151-A1 | THERAPEUTIC AURONES | AURKA, PIGS, PRF1 | RAB9A 2162/4885MAPT 3325/4885MEN1 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.