Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | STK17B | O94768 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10734520 | 0.89 | RAB9A (0.80) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL10734524 | 0.89 | RAB9A (0.80) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL10739409 | 0.88 | RAB9A (0.79) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL5308789 | 0.85 | RAB9A (0.73) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL5308793 | 0.85 | RAB9A (0.73) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL29537543 | 0.81 | RAB9A (0.68) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL11861138 | 0.81 | RAB9A (0.68) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL21082603 | 0.81 | RAB9A (0.68) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL21046440 | 0.79 | MEN1 (0.65) | RAB9AMEN1KMT2AMAPTPOLB | |
| SCHEMBL10730454 | 0.79 | RAB9A (0.68) | RAB9AMEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |