Metocinium

Metocinium

SCHEMBL2108327

C[N+](C)(C)CCOC(=O)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 8/20 0.74
CHRM1 P11229 8/20 0.74
CHRM3 P20309 7/20 0.74
CHRM4 P08173 5/20 0.74
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
POLB P06746 1/20 0.58
ALDH1A1 P00352 2/20 0.56
SCN1A P35498 2/20 0.51
SCN2A Q99250 2/20 0.51
SCN3A Q9NY46 2/20 0.51
CHRM5 P08912 2/20 0.51
CYP2D6 P10635 1/20 0.51
SLC6A3 Q01959 1/20 0.48
KCNH2 Q12809 1/20 0.48
GAA P10253 1/20 0.48
KDM4E B2RXH2 1/20 0.47
APOBEC3A P31941 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metocinium SCHEMBL2732726 0.98 CHRM2 (0.72) CHRM2CHRM1CHRM3CHRM4MEN1
Methylbenactyzium SCHEMBL669744 0.86 CHRM1 (0.97) CHRM2CHRM1CHRM3CHRM4MEN1
Methylbenactyzium SCHEMBL60901 0.85 CHRM1 (1.00) CHRM2CHRM1CHRM3CHRM4MEN1
Lachesine SCHEMBL1946024 0.85 CHRM1 (0.75) CHRM2CHRM1CHRM3CHRM4MEN1
Methylbenactyzium SCHEMBL8816404 0.85 CHRM1 (0.94) CHRM2CHRM1CHRM3CHRM4MEN1
SCHEMBL11363962 0.84 CHRM2 (0.55) CHRM2CHRM1CHRM3CHRM4MEN1
SCHEMBL8309422 0.84 CHRM2 (0.60) CHRM2CHRM1CHRM3CHRM4SCN1A
Lachesine SCHEMBL3638169 0.84 CHRM1 (0.73) CHRM2CHRM1CHRM3CHRM4MEN1
SCHEMBL11363241 0.83 CHRM2 (0.57) CHRM2CHRM1CHRM3CHRM4MEN1
Methylbenactyzium SCHEMBL8446490 0.83 CHRM1 (0.95) CHRM2CHRM1CHRM3CHRM4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-3654964-B1 COMPOSITION COMPRISING ATROPINE AND A MIOTIC AGENT AND ITS USE IN THE TREATMENT OF MYOPIA SEINDA PHARMACEUTICAL GUANGZHOU CORP (CN) 2024-04-24 EP disclosed
US-20230062844-A1 COMPOSITION AND METHODS FOR THE TREATMENT OF MYOPIA Seinda Pharmaceutical Guangzhou Corporation (CN) 2023-03-02 US disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-20200163951-A1 COMPOSITION AND METHODS FOR THE TREATMENT OF MYOPIA Seinda Pharmaceutical Guangzhou Corporation (CN) 2020-05-28 US disclosed
EP-3654964-A1 COMPOSITION AND METHODS FOR THE TREATMENT OF MYOPIA Alan Laboratories, Inc. (US) 2020-05-27 EP disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-7905852-B2 Skin-contacting-adhesive free dressing JENNINGS-SPRING BARBARA 2011-03-15 US disclosed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US disclosed
WO-2010024870-A1 SKIN-CONTACTING-ADHESIVE FREE DRESSING JENNINGS-SPRING BARBARA BROOKE (US) 2010-03-04 WO disclosed
US-20090005722-A1 Skin-contacting-adhesive free dressing JENNLNGS-SPRING BARBARA 2009-01-01 US disclosed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP disclosed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO disclosed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200163951-A1 COMPOSITION AND METHODS FOR THE TREATMENT OF MYOPIA CHRM3, CHRM2, MYOC CHRM2 2/4885CHRM1 13/4885CHRM3 1/4885
US-20230062844-A1 COMPOSITION AND METHODS FOR THE TREATMENT OF MYOPIA CHRM3, CHRM2, MYOC CHRM2 2/4885CHRM1 13/4885CHRM3 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.