Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 12/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.60 |
| ▸ | SCN1A | P35498 | 2/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metocinium SCHEMBL2108327 | 0.84 | CHRM2 (0.74) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| Metocinium SCHEMBL2732726 | 0.83 | CHRM2 (0.72) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL10029779 | 0.79 | CHRM2 (0.66) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL7022310 | 0.78 | CHRM2 (0.51) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL28352271 | 0.78 | CHRM2 (0.64) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL29156932 | 0.78 | CHRM2 (0.64) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL5072133 | 0.77 | CHRM2 (0.60) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL31256699 | 0.76 | CHRM2 (0.58) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL9588270 | 0.75 | ALDH1A1 (0.68) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| Aprofene SCHEMBL2354824 | 0.75 | CHRM2 (1.00) | CHRM2CHRM1CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004103357-A1 | COMPOSITIONS FOR THE TREATMENT OF REDUCED BLOOD FLOW | PHARMACIA CORPORATION (US) | 2004-12-02 | — | — | WO | disclosed |