SCHEMBL2108364

SCHEMBL2108364

CCOc1cccc(C(=O)c2cccc(OCC)c2OCC)c1OCC

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.49
GLA P06280 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
MAPT P10636 3/20 0.47
HTT P42858 1/20 0.47
KCNK3 O14649 1/20 0.46
KCNK9 Q9NPC2 1/20 0.46
RAB9A P51151 1/20 0.46
GAA P10253 2/20 0.45
LMNA P02545 2/20 0.45
MAPK1 P28482 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
TSHR P16473 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL206584 0.89 RAB9A (0.57) HCRTR1L3MBTL1GLAMEN1KMT2A
SCHEMBL3424538 0.87 MAPK1 (0.53) HCRTR1L3MBTL1GLAMEN1KMT2A
SCHEMBL29768766 0.87 MAPK1 (0.53) HCRTR1L3MBTL1GLAMEN1KMT2A
SCHEMBL690705 0.87 CYP3A4 (0.53) HCRTR1L3MBTL1GLAMEN1KMT2A
SCHEMBL3189724 0.86 TSHR (0.53) HCRTR1L3MBTL1GLAMEN1KMT2A
SCHEMBL27574878 0.86 HCRTR1 (0.49) HCRTR1L3MBTL1GLAMEN1KMT2A
SCHEMBL9653311 0.86 HCRTR1 (0.49) HCRTR1L3MBTL1GLAMEN1KMT2A
SCHEMBL20496475 0.85 LMNA (0.68) L3MBTL1GLARAB9ALMNAMAPK1
SCHEMBL29035604 0.84 HCRTR1 (0.47) HCRTR1L3MBTL1GLAMEN1KMT2A
SCHEMBL16950864 0.83 HCRTR1 (0.45) HCRTR1L3MBTL1GLAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130228950-A1 METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2013-09-05 US disclosed
US-8444899-B2 Methods and materials for fabricating microfluidic devices THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2013-05-21 US disclosed
EP-2537657-A2 Methods and materials for fabricating microfluidic devices The University of North Carolina at Chapel Hill (US) 2012-12-26 EP disclosed
US-20120256354-A1 METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2012-10-11 US disclosed
US-8158728-B2 Methods and materials for fabricating microfluidic devices THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2012-04-17 US disclosed
US-20090281250-A1 METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2009-11-12 US disclosed
EP-1922364-A2 METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES The University of North Carolina At Chapel Hill (US) 2008-05-21 EP disclosed
WO-2007021762-A2 METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2007-02-22 WO disclosed