Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295881 | 1.00 | GRIK1 (0.31) | GRIK1GRIK2 | |
| SCHEMBL9978452 | 0.79 | DGAT1 (0.38) | — | |
| SCHEMBL622757 | 0.78 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL622756 | 0.78 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL661765 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL663368 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL11028495 | 0.72 | TSHR (0.35) | — | |
| SCHEMBL14425429 | 0.69 | — | — | |
| SCHEMBL277198 | 0.69 | TSHR (0.36) | — | |
| SCHEMBL15592487 | 0.69 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158393-B2 | Polypeptide having esterase activity and recombinant esterase and use thereof | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AU) | 2012-04-17 | — | — | US | disclosed |
| CN-101351548-A | Novel polypeptide having esterase activity and recombinant esterase and use thereof | DSM FINE CHEM AUSTRIA GMBH (AT) | 2009-01-21 | — | — | CN | disclosed |