Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5605687 | 0.80 | MAPT (0.32) | DGAT1 | |
| SCHEMBL5264547 | 0.80 | MAPT (0.32) | DGAT1 | |
| SCHEMBL2108417 | 0.79 | GRIK1 (0.31) | — | |
| SCHEMBL295881 | 0.79 | GRIK1 (0.31) | — | |
| SCHEMBL16305496 | 0.73 | — | — | |
| SCHEMBL17617203 | 0.72 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL13350013 | 0.72 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL9911580 | 0.71 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL8161656 | 0.71 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL12168855 | 0.71 | DGAT1 (0.45) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148392-A1 | PROCESS FOR THE PREPARATION OF (2S,4S,5S,7S)-N-(2-CARBAMYL-2- METHYLPROPYL)-5-AMINO-4-HYDROXY-2,7-DIISOPROPYL-8-[4-METHOXY-3-(3- METHOXYPROPOXY)PHENYL]-OCTANAMIDE HEMIFUMARATE AND ITS INTERMEDIATES THEREOF | MSN LABORATORIES LIMITED (IN) | 2011-12-01 | — | — | WO | disclosed |