SCHEMBL2108443

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17496554	0.91	SIRT6 (0.42)	SIRT6P4HTMKDM4ENAPRTHCAR2
	SCHEMBL31379016	0.85	SIRT6 (0.46)	SIRT6P4HTMKDM4ENAPRTHCAR2
	SCHEMBL991368	0.85	SIRT6 (0.46)	SIRT6P4HTMKDM4ENAPRTHCAR2
	Formic Acid SCHEMBL2593977	0.82	SIRT6 (0.53)	SIRT6BACE1BACE2
	SCHEMBL10328670	0.82	SIRT6 (0.47)	SIRT6P4HTMKDM4ENAPRTHCAR2
	SCHEMBL841915	0.81	EPHX2 (0.46)	SIRT6ASPHBACE1BACE2L3MBTL1
	SCHEMBL2107109	0.81	MAPK1 (0.44)	SIRT6KDM4EBACE1BACE2ALDH1A1
	SCHEMBL1935667	0.81	SIRT6 (0.50)	SIRT6KDM4ENAPRTHCAR2BACE1
	SCHEMBL24214121	0.80	L3MBTL1 (0.41)	SIRT6P4HTMKDM4EASPHKDM8
	SCHEMBL7941192	0.78	SIRT6 (0.44)	SIRT6P4HTMKDM4ENAPRTHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.