⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21085097 | 0.86 | ALDH1A1 (0.30) | — | |
| SCHEMBL21085059 | 0.82 | — | — | |
| SCHEMBL21085023 | 0.81 | AKR1C3 (0.31) | — | |
| SCHEMBL21085049 | 0.80 | SLC18A3 (0.31) | — | |
| SCHEMBL1105462 | 0.78 | SHBG (0.37) | — | |
| SCHEMBL21409652 | 0.78 | SHBG (0.37) | — | |
| SCHEMBL9978993 | 0.76 | — | — | |
| SCHEMBL6662787 | 0.76 | SHBG (0.41) | — | |
| SCHEMBL6145227 | 0.76 | SHBG (0.41) | — | |
| SCHEMBL42926 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759749-B2 | Therapeutic agent for diabetes | JCR PHARMACEUTICALS CO., LTD. (JP) | 2020-09-01 | — | — | US | disclosed |
| EP-3508474-A1 | NOVEL THERAPEUTIC AGENT FOR DIABETES | JCR Pharmaceuticals Co., Ltd. (JP) | 2019-07-10 | — | — | EP | disclosed |
| US-20190202781-A1 | NOVEL THERAPEUTIC AGENT FOR DIABETES | JCR PHARMACEUTICALS CO., LTD. (JP) | 2019-07-04 | — | — | US | disclosed |