SCHEMBL210851

SCHEMBL210851

C=CCC(N)=C(C)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
FGFR4 P22455 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45577 1.00 ALDH1A1 (0.32) ALDH1A1TSHRFGFR4TDP1LMNA
SCHEMBL1201121 0.84 TDP1 (0.38) ALDH1A1TSHRFGFR4TDP1LMNA
SCHEMBL1635822 0.84 TDP1 (0.38) ALDH1A1TSHRFGFR4TDP1LMNA
SCHEMBL8927707 0.78 FNTA (0.34) TDP1
SCHEMBL14938405 0.77
SCHEMBL18755191 0.77 ALDH1A1 (0.30) ALDH1A1TSHRFGFR4
SCHEMBL517190 0.76 ALDH1A1 (0.35) ALDH1A1LMNA
SCHEMBL8760513 0.76 ALDH1A1 (0.35) ALDH1A1TSHRFGFR4LMNA
SCHEMBL8944182 0.76 ALDH1A1 (0.35) ALDH1A1LMNA
SCHEMBL362181 0.76 ALDH1A1 (0.35) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013054352-A1 PHARMACEUTICAL COMPOSITIONS OF IBUPROFEN AND FAMOTIDINE CADILA HEALTHCARE LIMITED (IN) 2013-04-18 WO claimed
EP-1694303-A1 TASTE MASKED PHARMACEUTICAL COMPOSITION COMPRISING PH SENSITIVE POLYMER COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-08-30 EP claimed
WO-2005055986-A1 TASTE MASKED PHARMACEUTICAL COMPOSITION COMPRISING PH SENSITIVE POLYMER COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-06-23 WO claimed
US-20050136115-A1 Taste masked pharmaceutical composition comprising pH sensitive polymer COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-06-23 US claimed
EP-1131057-B1 CUSHIONING WAX BEADS FOR MAKING SOLID SHAPED ARTICLES UNIV GENT (BE) 2005-04-20 EP claimed
US-11786476-B2 Oral dosage form UNIVERSITEIT GENT (BE) 2023-10-17 US disclosed
US-20220339857-A1 3D PRINTING DEVICE AND METHOD Triastek, Inc. (CN) 2022-10-27 US disclosed
US-11364674-B2 3D printing device and method Triastek, Inc. (CN) 2022-06-21 US disclosed
US-20210353548-A1 ORAL DOSAGE FORM UNIVERSITEIT GENT (BE) 2021-11-18 US disclosed
EP-3892263-A1 ORAL DOSAGE FORM Universiteit Gent (BE) 2021-10-13 EP disclosed
US-11065207-B2 Oral dosage form UNIVERSITEIT GENT (BE) 2021-07-20 US disclosed
US-20210154910-A1 3D PRINTING DEVICE AND METHOD Triastek, Inc. (CN) 2021-05-27 US disclosed
WO-2008011426-A2 METHODS AND MEDICAMENTS FOR ADMINISTRATION OF IBUPROFEN HORIZON THERAPEUTICS, INC. (US) 2008-01-24 WO disclosed
US-20080021078-A1 Methods and medicaments for administration of ibuprofen HORIZON THERAPEUTICS, INC. (US) 2008-01-24 US disclosed
CN-1221281-C Oral, nasal and pulmonary dosage formulations of copolymer1 YEDA RES & DEV (IL) 2005-10-05 CN disclosed
CN-1424915-A Oral, nasal and pulmonary dosage formulations of copolymer1 YEDA RES DEV CO LTD AT THE WEI (IL) 2003-06-18 CN disclosed
US-6379706-B2 WHICH CONTAIN AT LEAST ONE ROUNDING AGENT REQUIRED TO PRODUCE EXTRUSION PELLETS WHICH ACTS AS A RETARDANT OR DISINTEGRATION-RETARDING AGENT WHICH IS SUITABLE FOR DELAYING THE RELEASE TIME OF ACTIVE SUBSTANCES ROCHE DIAGNOSTICS GMBH (DE) 2002-04-30 US disclosed
WO-2002017877-A2 CONTROLLED RELEASE PHARMACEUTICAL PELLET COMPOSITIONS FOR REDUCING SIDE EFFECTS OF DRUGS UNIVERSITEIT GENT (BE) 2002-03-07 WO disclosed
US-20010004458-A1 Rapidly disintegrating pellets ROCHE DIAGNOSTICS GMBH 2001-06-21 US disclosed
US-6224909-B1 DRUG MIXTURE OF ACTIVE MATERIALS, RELEASE RETARDERS, TABLET DISINTEGRANT, SURFACTANT AND BINDER ROCHE DIAGNOSTICS GMBH (DE) 2001-05-01 US disclosed