SCHEMBL1201121

SCHEMBL1201121

C=CC/C(N)=C(/C)C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
FGFR4 P22455 1/20 0.33
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1635822 1.00 TDP1 (0.38) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL210851 0.84 ALDH1A1 (0.32) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL45577 0.84 ALDH1A1 (0.32) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL25416543 0.81 TDP1 (0.38) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL170138 0.81 TDP1 (0.38) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL504358 0.79 TDP1 (0.36) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL14938405 0.79
SCHEMBL11411969 0.77 TDP1 (0.31) TDP1
SCHEMBL5683864 0.76 TDP1 (0.33) TDP1
SCHEMBL18660282 0.76 TDP1 (0.33) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667334-A Novel methacrylate copolymers and compositions comprising the same 赢创运营有限公司 2023-01-31 CN claimed
EP-2753650-B1 POLYMERIC AGENTS THAT IMPROVE PRIMARY WASHING EFFICIENCY HENKEL AG & CO KGAA (DE) 2020-04-08 EP claimed
WO-2016108719-A1 PROCESS FOR PREPARING FUNCTIONALIZED DIENE (CO) POLYMERS BY USING INITIATOR PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2016-07-07 WO claimed
WO-2016108715-A1 DILITHIUM INITIATOR FOR ANIONIC POLYMERIZATION PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2016-07-07 WO claimed
US-20140187461-A1 POLYMERIC AGENTS THAT IMPROVE PRIMARY WASHING EFFICIENCY FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2014-07-03 US claimed
EP-2313440-B1 METHOD FOR SYNTHESIZING AMPHIPHILIC GRADIENT COPOLYMERS SOLUBLE IN AN ALKALINE MEDIUM ARKEMA FRANCE (FR) 2013-07-17 EP claimed
US-20110136963-A1 METHOD FOR SNYTHESIZING AMPHIPHILIC GRADIENT COPOLYMERS SOLUBLE IN AN ALKALINE MEDIUM ARKEMA FRANCE (FR) 2011-06-09 US claimed
US-7700693-B2 Conjugated diene rubber compostion, process for producing the same and rubber vulcanizate ZEON CORPORATION (JP) 2010-04-20 US claimed
EP-1583781-B1 GRADIENT COPOLYMERS SOLUBLE OR AT LEAST DISPERSIBLE IN WATER AS WELL AS IN ORGANIC SOLVENTS ARKEMA FRANCE (FR) 2008-07-02 EP claimed
EP-1490016-B1 CATIONIC POLYMERS AND THE USE THEREOF IN COSMETIC FORMULATIONS BASF AG (DE) 2007-06-06 EP claimed
US-7198882-B2 Adhesion promoting polymeric materials and planographic printing elements containing them EASTMAN KODAK COMPANY (US) 2007-04-03 US claimed
US-20060058467-A1 Gradient copolymers soluble or at least dispersible in water as well as in organic solvents ARKEMA FRANCE (FR) 2006-03-16 US claimed
US-20050095536-A1 Adhesion promoting polymeric materials and planographic printing elements containing them EASTMAN KODAK COMPANY 2005-05-05 US claimed
US-20050084469-A1 Cationic polymers and the use thereof in cosmetic formulations BASF AKTIENGESELLSCHAFT (DE) 2005-04-21 US claimed
EP-0373739-B1 IMPROVED ADHESIVE EMULSION COMPOSITION AND ACCOMPANYING COATED SUBSTRATES, SUCH AS PREPASTED WALL COVERINGS Borden, Inc. (US) 1992-12-16 EP claimed
US-4479879-A CATIONIC POLYMER FLOCCULANTS, ANIONIC POLYMER FLOCCULANTS KURITA WATER INDUSTRIES LTD. (JP) 1984-10-30 US claimed
US-4111859-A METHOD OF PREPARATION OF ION EXCHANGERS BY ALKYLATION AND HYDROXYALKYLATION OF POLYMERIC HYDROPHILIC ANION EXCHANGERS CESKOSLOVENSKA AKADEMIE VED (CS) 1978-09-05 US claimed
US-4097420-A Method for preparation of macroporous amphoteric ion exchangers with highly crosslinked hydrophilic polymeric matrix CESKOSLOVENSKA AKADEMIE VED (CS) 1978-06-27 US claimed
JP-61054300-A None JP disclosed
US-4097420-A Method for preparation of macroporous amphoteric ion exchangers with highly crosslinked hydrophilic polymeric matrix CESKOSLOVENSKA AKADEMIE VED (CS) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050084469-A1 Cationic polymers and the use thereof in cosmetic formulations PARN, CUTA, PARG TDP1 1000/4885ALDH1A1 4197/4885TSHR 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.