SCHEMBL1635822

SCHEMBL1635822

C=CCC(N)=C(C)C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
FGFR4 P22455 1/20 0.33
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1201121 1.00 TDP1 (0.38) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL210851 0.84 ALDH1A1 (0.32) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL45577 0.84 ALDH1A1 (0.32) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL25416543 0.81 TDP1 (0.38) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL170138 0.81 TDP1 (0.38) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL504358 0.79 TDP1 (0.36) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL14938405 0.79
SCHEMBL11411969 0.77 TDP1 (0.31) TDP1
SCHEMBL5683864 0.76 TDP1 (0.33) TDP1
SCHEMBL18660282 0.76 TDP1 (0.33) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130302392-A1 HYDROGEL MICROCAPSULES HERCULES LLC 2013-11-14 US claimed
EP-2646002-A2 HYDROGEL MICROCAPSULES Isp Investments Inc. (US) 2013-10-09 EP claimed
EP-2313440-B1 METHOD FOR SYNTHESIZING AMPHIPHILIC GRADIENT COPOLYMERS SOLUBLE IN AN ALKALINE MEDIUM ARKEMA FRANCE (FR) 2013-07-17 EP claimed
CN-101258232-B Delivery system for releasing silicone ingredients DOW CORNING 2013-02-06 CN claimed
WO-2012075293-A2 HYDROGEL MICROCAPSULES ISP INVESTMENTS INC. (US) 2012-06-07 WO claimed
CN-102482619-A Cationic polymer thickeners SPCM SA 2012-05-30 CN claimed
CN-102190760-A Silicon-organic graft copolymers containing nitrogen EVONIK GOLDSCHMIDT GMBH 2011-09-21 CN claimed
EP-1740302-B1 PARTICULATE COMPOSITIONS AND THEIR MANUFACTURE CIBA SPEC CHEM WATER TREAT LTD (GB) 2010-06-23 EP claimed
CN-101258232-A Delivery system for releasing silicone ingredients DOW CORNING (US) 2008-09-03 CN claimed
EP-1740302-A1 PARTICULATE COMPOSITIONS AND THEIR MANUFACTURE Ciba Specialty Chemicals Water Treatments Limited (GB) 2007-01-10 EP claimed
CN-1294170-C Production of Aqueous Dispersions of Cationic Homopolymers and Copolymers Using Amphoteric Protective Colloids BASF AG (DE) 2007-01-10 CN claimed
WO-2005105291-A1 PARTICULATE COMPOSITIONS AND THEIR MANUFACTURE CIBA SPECIALTY CHEMICALS WATER TREATMENT LIMITED (GB) 2005-11-10 WO claimed
CN-1088777-C Production of filled paper and compositions for use in this CIBA SPEC CHEM WATER TREAT LTD (GB) 2002-08-07 CN claimed
US-6201093-B1 MERCAPTO-FUNCTIONAL POLYSILOXANES MODIFIED WITH ETHENICALLY UNSATURATED COMPOUNDS CONTAINING AMINO GROUPS; USE AS TEXTILE FINISHING AIDS, SURFACTANTS AND EMULSIFIERS HUELS AKTIENGESELLSCHAFT (DE) 2001-03-13 US claimed
US-5358566-A Comprising polymer salt from polycarboxylic acid and nitrogenous acrylic polymer; preventing slump loss SANDOZ LTD. (CH) 1994-10-25 US claimed
US-5013468-A Terpolymer of aminoalkyl acrylamide or acrylate, an acrylamide and an acrylate TEXACO INC. (US) 1991-05-07 US claimed
US-4941985-A AN ALKYL METHACRYLATE POLYMER, AN AROMATIC NITROSO COMPOUND TEXACO INC. (US) 1990-07-17 US claimed
EP-0077618-B1 ADHESIVES FOR PREPASTED WALLCOVERINGS Ciba Specialty Chemicals Water Treatments Limited (GB) 1986-12-17 EP claimed
EP-0077618-A1 Adhesives for prepasted wallcoverings Ciba Specialty Chemicals Water Treatments Limited (GB) 1983-04-27 EP claimed
EP-3617257-B1 SALT TOLERANT ANION EXCHANGE MEDIUM PALL CORP (US) 2024-01-31 EP disclosed
US-11717471-B2 Hydrogel microcapsules ISP INVESTMENTS LLC (US) 2023-08-08 US disclosed
CN-114144553-A Composite fiber of cellulose fiber and inorganic particle and method for producing same 日本制纸株式会社 2022-03-04 CN disclosed
EP-3617256-B1 SALT TOLERANT POROUS MEDIUM PALL CORP (US) 2022-01-19 EP disclosed
US-11045773-B2 Salt tolerant porous medium PALL CORPORATION (US) 2021-06-29 US disclosed
CN-111989433-A Composite fiber of cellulose fiber and inorganic particle and method for producing same 日本制纸株式会社 2020-11-24 CN disclosed
CN-107429154-B Improved poly (vinyl caprolactam) kinetic gas hydrate inhibitors and methods of making the same 亨斯迈石油化学有限责任公司 2020-11-20 CN disclosed
US-10737259-B2 Salt tolerant anion exchange medium PALL CORPORATION (US) 2020-08-11 US disclosed
US-20200070104-A1 SALT TOLERANT POROUS MEDIUM PALL CORPORATION (US) 2020-03-05 US disclosed
US-20200070140-A1 SALT TOLERANT ANION EXCHANGE MEDIUM PALL CORPORATION (US) 2020-03-05 US disclosed
EP-3617256-A1 SALT TOLERANT POROUS MEDIUM Pall Corporation (US) 2020-03-04 EP disclosed
EP-3617257-A1 SALT TOLERANT ANION EXCHANGE MEDIUM Pall Corporation (US) 2020-03-04 EP disclosed
CN-102482619-B Cationic polymer thickeners S.P.C.M. S.A. (FR) 2016-04-20 CN disclosed
US-20130302392-A1 HYDROGEL MICROCAPSULES HERCULES LLC 2013-11-14 US disclosed
EP-2646002-A2 HYDROGEL MICROCAPSULES Isp Investments Inc. (US) 2013-10-09 EP disclosed
CN-101258232-B Delivery system for releasing silicone ingredients DOW CORNING 2013-02-06 CN disclosed
CN-102046701-B Emulsions of boron crosslinked organopolysiloxanes and their use in personal care compositions DOW CORNING 2012-11-21 CN disclosed
WO-2012075293-A2 HYDROGEL MICROCAPSULES ISP INVESTMENTS INC. (US) 2012-06-07 WO disclosed
CN-102482619-A Cationic polymer thickeners SPCM SA 2012-05-30 CN disclosed
CN-102197058-A Silicone-organic composite emulsions in personal care applications DOW CORNING 2011-09-21 CN disclosed
CN-102046701-A Emulsions of boron crosslinked organopolysiloxanes and their use in personal care compositions DOW CORNING 2011-05-04 CN disclosed
US-7932191-B2 Particulate compositions and their manufacture CIBA SPECIALTY CHEMICALS WATER TREATMENTS LTD. (GB) 2011-04-26 US disclosed
EP-2265105-A1 ENCAPSULATED PHASE CHANGE MATERIALS IN SEED COATINGS BASF SE (DE) 2010-12-29 EP disclosed
EP-1740302-B1 PARTICULATE COMPOSITIONS AND THEIR MANUFACTURE CIBA SPEC CHEM WATER TREAT LTD (GB) 2010-06-23 EP disclosed
CN-100594022-C Hair treatment method and its use OREAL 2010-03-17 CN disclosed
CN-100588388-C Cosmetic composition, method for using the same composition and use of the same composition OREAL 2010-02-10 CN disclosed
CN-100581526-C Dyeing composition for keratinous fibers comprising an oxyethylene rapeseed fatty acid amide OREAL 2010-01-20 CN disclosed
WO-2009112360-A1 ENCAPSULATED PHASE CHANGE MATERIALS IN SEED COATINGS BASF SE (DE) 2009-09-17 WO disclosed
US-20090227451-A1 Encapsulated phase change materials in seed coatings CIBA CORP. 2009-09-10 US disclosed
CN-100482200-C Cosmetic composition, method for using the same composition and use of the same composition OREAL (FR) 2009-04-29 CN disclosed
CN-101310224-A Polymeric colour electrophotographic toner compositions and process of preparing polymeric electrophotographic toner composition CIBA HOLDING INC (CH) 2008-11-19 CN disclosed
CN-101258232-A Delivery system for releasing silicone ingredients DOW CORNING (US) 2008-09-03 CN disclosed
CN-100360437-C Method for treatment of aqueous streams comprising biosolids DU PONT (US) 2008-01-09 CN disclosed
CN-100344462-C Ink jet recording medium MITSUI CHEMICALS INC (JP) 2007-10-24 CN disclosed
US-20070224899-A1 Particulate Compositions and Their Manufacture CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2007-09-27 US disclosed
EP-1740302-A1 PARTICULATE COMPOSITIONS AND THEIR MANUFACTURE Ciba Specialty Chemicals Water Treatments Limited (GB) 2007-01-10 EP disclosed
CN-1294170-C Production of Aqueous Dispersions of Cationic Homopolymers and Copolymers Using Amphoteric Protective Colloids BASF AG (DE) 2007-01-10 CN disclosed
CN-1882308-A Thickened hair treatment containing water glass WELLA AG (DE) 2006-12-20 CN disclosed
CN-1762327-A Use for the cosmetic treatment of keratinous material of not sticky compositions based on electrophilic monomers and non-silicon polymers OREAL (FR) 2006-04-26 CN disclosed
CN-1751075-A Graft polymers and use thereof in cosmetic formulations BASF AG (DE) 2006-03-22 CN disclosed
WO-2005105291-A1 PARTICULATE COMPOSITIONS AND THEIR MANUFACTURE CIBA SPECIALTY CHEMICALS WATER TREATMENT LIMITED (GB) 2005-11-10 WO disclosed
CN-1225233-C Aqueous composition for bleaching keratin fibers instantaneously OREAL (FR) 2005-11-02 CN disclosed
CN-1682683-A Hair treatment method and its use OREAL (FR) 2005-10-19 CN disclosed
CN-1678649-A The production of aqueous dispersions of cationic homo- and copolymers using amphoteric protective colloids BASF AG (DE) 2005-10-05 CN disclosed
CN-1675070-A Ink jet recording medium MITSUI CHEMICALS INC (JP) 2005-09-28 CN disclosed
CN-1636541-A Cosmetic composition, method for using the same composition and use of the same composition OREAL (FR) 2005-07-13 CN disclosed
CN-1636540-A Cosmetic composition, method for using the same composition and use of the same composition OREAL (FR) 2005-07-13 CN disclosed
CN-1620279-A Dyeing composition for keratinous fibers comprising an oxyethylene rapeseed fatty acid amide OREAL (FR) 2005-05-25 CN disclosed
WO-2005018679-A1 A HYBRID OF FREE-BASE AMLODIPINE WITH A LAYERED SILICATE AND A PROCESS FOR PREPARING THE SAME NANOHYBRID CO., LTD. (KR) 2005-03-03 WO disclosed
CN-1572282-A Hair cosmetic composition comprising tridecyl trimellitate and a fixing polymer OREAL (FR) 2005-02-02 CN disclosed
CN-1572285-A A hair-treatment composition based on isoeicosane and silicone fixing polyurethane OREAL (FR) 2005-02-02 CN disclosed
CN-1572281-A A hair-treatment composition based on isoeicosane and non-silicone fixing polymer OREAL (FR) 2005-02-02 CN disclosed
CN-1183069-C Method for preventing or delaying formation of gas hydrates ISP 2005-01-05 CN disclosed
CN-1099281-C Cosmetic fixative composition providing shine OREAL (FR) 2003-01-22 CN disclosed
CN-1334787-A Method for preventing or retarding formation of gas hydrates ISP INVESTMENTS INC (US) 2002-02-06 CN disclosed
CN-1303355-A Method for treatment of aqueous streams comprising biosolids DU PONT (US) 2001-07-11 CN disclosed
US-6201093-B1 MERCAPTO-FUNCTIONAL POLYSILOXANES MODIFIED WITH ETHENICALLY UNSATURATED COMPOUNDS CONTAINING AMINO GROUPS; USE AS TEXTILE FINISHING AIDS, SURFACTANTS AND EMULSIFIERS HUELS AKTIENGESELLSCHAFT (DE) 2001-03-13 US disclosed
CN-1270022-A Anhydrous composition for bleaching keratin fibers OREAL (FR) 2000-10-18 CN disclosed
CN-1270020-A Aqueous composition for bleaching keratin fibers instantaneously OREAL (FR) 2000-10-18 CN disclosed
CN-1204255-A Conditioning shampoo compositions having improved stability PROCTER & GAMBLE (US) 1999-01-06 CN disclosed
CN-1204248-A Conditioning shampoo compositions PROCTER & GAMBLE (US) 1999-01-06 CN disclosed
CN-1200023-A Hair styling shampoos containing organic oil PROCTER & GAMBLE (US) 1998-11-25 CN disclosed
CN-1180308-A Cosmetic composition for setting and glossing OREAL (FR) 1998-04-29 CN disclosed
US-5358566-A Comprising polymer salt from polycarboxylic acid and nitrogenous acrylic polymer; preventing slump loss SANDOZ LTD. (CH) 1994-10-25 US disclosed
US-5358566-A Comprising polymer salt from polycarboxylic acid and nitrogenous acrylic polymer; preventing slump loss SANDOZ LTD. (CH) 1994-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11717471-B2 Hydrogel microcapsules MITF, DSG1, SHH TDP1 1869/4885ALDH1A1 1165/4885TSHR 2621/4885
US-20130302392-A1 HYDROGEL MICROCAPSULES MITF, DSG1, SHH TDP1 1869/4885ALDH1A1 1165/4885TSHR 2621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.