Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 4/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 4/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21085021 | 0.84 | SLC6A12 (0.39) | SLC6A12SLC6A11SLC6A13GABRR1GABRR2 | |
| SCHEMBL21085088 | 0.82 | GABRR1 (0.34) | GABRR1GABRR2ALDH1A1 | |
| SCHEMBL21085031 | 0.81 | SLC6A12 (0.43) | SLC6A12SLC6A11SLC6A13GABRR1HSD11B1 | |
| SCHEMBL21085012 | 0.81 | HSD17B10 (0.35) | GABRR1GABRR2MEN1KMT2ATSHR | |
| SCHEMBL21085017 | 0.78 | GABRR1 (0.32) | GABRR1GABRR2 | |
| SCHEMBL21085145 | 0.76 | SLC6A12 (0.39) | SLC6A12SLC6A11SLC6A13GABRR1SLC6A1 | |
| SCHEMBL21085029 | 0.76 | POLB (0.31) | GABRR1GABRR2 | |
| SCHEMBL21085075 | 0.73 | SLC6A12 (0.40) | SLC6A12SLC6A11SLC6A13GABRR1SLC6A1 | |
| SCHEMBL9800052 | 0.73 | KDM4E (0.38) | GABRR1SLC1A2ALDH1A1 | |
| SCHEMBL22902378 | 0.72 | SLC6A12 (0.43) | SLC6A12SLC6A11SLC6A13GABRR1GABRR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759749-B2 | Therapeutic agent for diabetes | JCR PHARMACEUTICALS CO., LTD. (JP) | 2020-09-01 | — | — | US | disclosed |
| EP-3508474-A1 | NOVEL THERAPEUTIC AGENT FOR DIABETES | JCR Pharmaceuticals Co., Ltd. (JP) | 2019-07-10 | — | — | EP | disclosed |
| US-20190202781-A1 | NOVEL THERAPEUTIC AGENT FOR DIABETES | JCR PHARMACEUTICALS CO., LTD. (JP) | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190202781-A1 | NOVEL THERAPEUTIC AGENT FOR DIABETES | GPR119, IAPP, DPP4 | SLC6A12 1837/4885SLC6A11 1410/4885SLC6A13 2070/4885 |
| US-10759749-B2 | Therapeutic agent for diabetes | GPR119, IAPP, DPP4 | SLC6A12 925/4885SLC6A11 1206/4885SLC6A13 1892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.