SCHEMBL21085145

SCHEMBL21085145

O=C(O)CC1CC[CH]CC1CO

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A12 P48065 5/20 0.39
SLC6A11 P48066 5/20 0.39
SLC6A13 Q9NSD5 5/20 0.39
SLC6A1 P30531 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRB2 P47870 2/20 0.31
GABRA1 P14867 1/20 0.31
GABRR1 P24046 1/20 0.31
GABRA4 P48169 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21085031 0.90 SLC6A12 (0.43) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5
SCHEMBL21085058 0.85 SLC6A12 (0.36) SLC6A12SLC6A11SLC6A13
SCHEMBL21085126 0.81 HSD17B10 (0.35)
SCHEMBL6438991 0.80
SCHEMBL21085075 0.78 SLC6A12 (0.40) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5
SCHEMBL21085149 0.76 SLC6A12 (0.39) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5
SCHEMBL21085021 0.76 SLC6A12 (0.39) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5
SCHEMBL21085066 0.75 HSD11B1 (0.39) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5
SCHEMBL5957597 0.74
SCHEMBL23227518 0.74 SLC6A12 (0.44) SLC6A12SLC6A11SLC6A13SLC6A1GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10759749-B2 Therapeutic agent for diabetes JCR PHARMACEUTICALS CO., LTD. (JP) 2020-09-01 US disclosed
EP-3508474-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES JCR Pharmaceuticals Co., Ltd. (JP) 2019-07-10 EP disclosed
US-20190202781-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES JCR PHARMACEUTICALS CO., LTD. (JP) 2019-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202781-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES GPR119, IAPP, DPP4 SLC6A12 1837/4885SLC6A11 1410/4885SLC6A13 2070/4885
US-10759749-B2 Therapeutic agent for diabetes GPR119, IAPP, DPP4 SLC6A12 925/4885SLC6A11 1206/4885SLC6A13 1892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.