Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Favipiravir. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Favipiravir SCHEMBL587913 | 0.98 | LCK (0.34) | LCKKMT2AMEN1PDPK1ADORA3 | |
| Favipiravir SCHEMBL30725561 | 0.96 | LCK (0.33) | LCKKMT2AMEN1PDPK1ADORA3 | |
| Favipiravir SCHEMBL28964779 | 0.85 | LMNA (0.32) | — | |
| SCHEMBL5269681 | 0.82 | PLAU (0.33) | LCKKMT2APDPK1ADORA3TSHR | |
| SCHEMBL31259490 | 0.82 | PLAU (0.33) | LCKKMT2APDPK1ADORA3TSHR | |
| Favipiravir SCHEMBL28952948 | 0.81 | PARP1 (0.38) | — | |
| SCHEMBL28398570 | 0.80 | KDM4E (0.37) | KMT2AMEN1TSHR | |
| SCHEMBL6376447 | 0.80 | KMT2A (0.32) | LCKKMT2AMEN1PDPK1ADORA3 | |
| SCHEMBL29733656 | 0.80 | KMT2A (0.32) | LCKKMT2AMEN1PDPK1ADORA3 | |
| SCHEMBL25028569 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019131223-A1 | METHOD FOR PRODUCING FREEZE-DRIED FORMULATION | 富士フイルム富山化学株式会社 | 2019-07-04 | — | — | WO | disclosed |