SCHEMBL2108618

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9577155	0.89	SMN1; SMN2 (0.41)	RCE1KMT2ASMN1; SMN2TDP1TSHR
	SCHEMBL9497399	0.89	SMN1; SMN2 (0.41)	RCE1KMT2ASMN1; SMN2TDP1TSHR
	SCHEMBL1776277	0.82	SMN1; SMN2 (0.43)	RCE1KMT2ASMN1; SMN2TDP1TSHR
	SCHEMBL15602691	0.81	SMN1; SMN2 (0.38)	RCE1MAPTKMT2ASMN1; SMN2TDP1
	SCHEMBL16177752	0.81	BCHE (0.39)	RCE1SMN1; SMN2TDP1TSHRBCHE
	SCHEMBL22490406	0.80	MEN1 (0.40)	RCE1KMT2ASMN1; SMN2TDP1TSHR
	SCHEMBL9685558	0.78	BCHE (0.42)	KMT2ABCHEALDH1A1MEN1
	SCHEMBL9684154	0.78	BCHE (0.42)	KMT2ABCHEALDH1A1MEN1
	SCHEMBL9685612	0.78	BCHE (0.42)	KMT2ABCHEALDH1A1MEN1
	SCHEMBL10288428	0.78	SMN1; SMN2 (0.36)	RCE1KMT2ASMN1; SMN2TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.