Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577155 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1776277 | 0.92 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15602691 | 0.91 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2108618 | 0.89 | RCE1 (0.46) | SMN1; SMN2TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10288428 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16177752 | 0.87 | BCHE (0.39) | SMN1; SMN2TSHRTDP1RCE1L3MBTL1 | |
| SCHEMBL9685360 | 0.86 | MAPT (0.39) | TDP1L3MBTL1BCHE | |
| SCHEMBL17006171 | 0.86 | LTA4H (0.38) | SMN1; SMN2TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16370105 | 0.86 | SLC1A3 (0.39) | SMN1; SMN2TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL22490406 | 0.86 | MEN1 (0.40) | SMN1; SMN2TSHRSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266703-A | Optically active isoxazole derivatives | DAISO CO., LTD. (JP) | 1993-11-30 | — | — | US | disclosed |
| US-5220074-A | Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same | DAISO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| US-5210201-A | Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same | DAISO CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5198588-A | OPTICALLY ACTIVE ISOXAZOLE DERIVATIVES AND INTERMEDIATES FOR PREPARATION THEREOF | DAISO CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0439129-A2 | Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same | Daiso Co., Ltd. (JP) | 1991-07-31 | — | — | EP | disclosed |