Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LPO | P22079 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FGB | P02675 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942970 | 0.84 | L3MBTL1 (0.47) | KDM4EL3MBTL1LPOCYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL25338117 | 0.82 | L3MBTL1 (0.46) | KDM4EL3MBTL1LPOCYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL27953560 | 0.82 | L3MBTL1 (0.46) | KDM4EL3MBTL1LPOCYP2D6MAPT | |
| Bromide SCHEMBL28223816 | 0.82 | L3MBTL1 (0.46) | KDM4EL3MBTL1LPOCYP2D6MAPT | |
| Water SCHEMBL31566367 | 0.82 | L3MBTL1 (0.46) | KDM4EL3MBTL1LPOCYP2D6MAPT | |
| SCHEMBL14060930 | 0.81 | KDM4E (0.41) | KDM4EL3MBTL1LPOCYP2D6MAPT | |
| Bromide SCHEMBL31511741 | 0.81 | L3MBTL1 (0.45) | KDM4EL3MBTL1LPOCYP2D6MAPT | |
| Bromide SCHEMBL28540808 | 0.79 | L3MBTL1 (0.41) | KDM4EL3MBTL1LPOCYP2D6MAPT | |
| SCHEMBL17385605 | 0.78 | KDM4E (0.50) | KDM4EL3MBTL1LPOCYP2D6MAPT | |
| SCHEMBL28702194 | 0.78 | TLR8 (0.41) | KDM4EL3MBTL1LPOCYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968963-B1 | SUBSTITUTED PROPIOLIC ACID AMIDES AND THEIR USE FOR PRODUCING ANALGESICS | GRUENENTHAL GMBH (DE) | 2011-10-05 | — | — | EP | disclosed |