Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 3/20 | 0.64 |
| ▸ | SLC6A3 known ✓ | Q01959 | 3/20 | 0.64 |
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.64 |
| ▸ | ADRA1A known ✓ | P35348 | 2/20 | 0.64 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.64 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.64 |
| ▸ | ADRA1D known ✓ | P25100 | 1/20 | 0.64 |
| ▸ | ADRA1B known ✓ | P35368 | 1/20 | 0.64 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | DRD2 | P14416 | 3/20 | 0.64 |
| ▸ | DRD3 | P35462 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL20553882 | 1.00 | KDM4E (0.64) | KDM4EMAPTALOX15MAPK1RECQL | |
| SCHEMBL110644 | 0.97 | KDM4E (0.67) | KDM4EMAPTALOX15MAPK1RECQL | |
| SCHEMBL29359577 | 0.97 | KDM4E (0.67) | KDM4EMAPTALOX15MAPK1RECQL | |
| Hydrochloric Acid SCHEMBL5071235 | 0.95 | KDM4E (0.68) | KDM4EMAPTALOX15MAPK1RECQL | |
| Hydrochloric Acid SCHEMBL30964291 | 0.95 | KDM4E (0.68) | KDM4EMAPTALOX15MAPK1RECQL | |
| Acetic Acid SCHEMBL27634531 | 0.85 | KDM4E (0.58) | KDM4EMAPTALOX15MAPK1RECQL | |
| Tromethamine SCHEMBL952901 | 0.83 | KDM4E (0.52) | KDM4EMAPTALOX15MAPK1RECQL | |
| Dopamine SCHEMBL30960386 | 0.81 | KDM4E (0.95) | KDM4EMAPTALOX15MAPK1RECQL | |
| Dopamine SCHEMBL3769932 | 0.81 | KDM4E (0.95) | KDM4EMAPTALOX15MAPK1RECQL | |
| Bromide SCHEMBL1469280 | 0.79 | CA2 (0.55) | ALOX15HSD17B10CYP2D6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250276107-A1 | HYDROGEL SYSTEMS AND METHODS FOR TREATING FISTULA AND OTHER INDICATIONS | TERASAKI INSTITUTE FOR BIOMEDICAL INNOVATION (US) | 2025-09-04 | — | — | US | claimed |
| CN-117503991-A | Cellulose collagen wound hydrogel dressing and preparation method thereof | 湖南安慕医疗器械有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-114835601-B | Multifunctional surfactant fracturing fluid thickening agent with oil displacement function and preparation method thereof | 西南石油大学 | 2023-09-22 | — | — | CN | claimed |
| CN-116059156-B | Double-layer network hydrogel microneedle and preparation method and application thereof | 四川大学 | 2023-06-20 | — | — | CN | claimed |
| CN-116059156-A | Double-layer network hydrogel microneedle and preparation method and application thereof | 四川大学 | 2023-05-05 | — | — | CN | claimed |
| CN-114835601-A | Multifunctional surfactant fracturing fluid thickening agent with oil displacement function and preparation method thereof | 西南石油大学 | 2022-08-02 | — | — | CN | claimed |
| CN-112843327-A | PH-responsive double-cross mussel bionic adhesive intelligent drug-loaded hydrogel and preparation method and application thereof | 四川大学 | 2021-05-28 | — | — | CN | claimed |
| EP-0290442-A4 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. | CHEMEX PHARMACEUTICALS INC (US) | 1990-07-03 | — | — | EP | claimed |
| EP-0290442-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-11-17 | — | — | EP | claimed |
| WO-1988003805-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | claimed |
| US-20250276107-A1 | HYDROGEL SYSTEMS AND METHODS FOR TREATING FISTULA AND OTHER INDICATIONS | TERASAKI INSTITUTE FOR BIOMEDICAL INNOVATION (US) | 2025-09-04 | — | — | US | disclosed |
| CN-117503991-A | Cellulose collagen wound hydrogel dressing and preparation method thereof | 湖南安慕医疗器械有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-114835601-B | Multifunctional surfactant fracturing fluid thickening agent with oil displacement function and preparation method thereof | 西南石油大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-116059156-B | Double-layer network hydrogel microneedle and preparation method and application thereof | 四川大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-116059156-A | Double-layer network hydrogel microneedle and preparation method and application thereof | 四川大学 | 2023-05-05 | — | — | CN | disclosed |
| US-5830904-A | Lobeline compounds as a treatment for psychostimulant abuse and withdrawal, and for eating disorders | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1998-11-03 | — | — | US | disclosed |
| US-5804163-A | Contrast agents for magnetic resonance imaging aminosaccharide | MAGNETIC RESEARCH, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| US-5330743-A | Aminosaccharide contrast agents for magnetic resonance images | MAGNETIC RESEARCH, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| US-4647660-A | 3-acylamino-2-oxo-1-azetidinesulfonic acids | E. R. SQUIBB & SONS, INC. (US) | 1987-03-03 | — | — | US | disclosed |
| EP-0200159-A2 | 3-Acylamino-2-oxo-1-azetidinesulfonic acids | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |