SCHEMBL110644

SCHEMBL110644

NCc1ccc(O)c(O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.67
MAPT P10636 6/20 0.67
ALOX15 P16050 5/20 0.67
MAPK1 P28482 4/20 0.67
RECQL P46063 4/20 0.67
TDP1 Q9NUW8 4/20 0.67
ALDH1A1 P00352 4/20 0.67
HIF1A Q16665 4/20 0.67
HSD17B10 Q99714 4/20 0.67
DRD2 P14416 3/20 0.67
SLC6A2 P23975 3/20 0.67
DRD3 P35462 3/20 0.67
SLC6A3 Q01959 3/20 0.67
TP53 P04637 3/20 0.67
THPO P40225 3/20 0.67
ADRA2A P08913 2/20 0.67
DRD1 P21728 2/20 0.67
DRD4 P21917 2/20 0.67
DRD5 P21918 2/20 0.67
CYP2D6 P10635 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29359577 1.00 KDM4E (0.67) KDM4EMAPTALOX15MAPK1RECQL
Hydrochloric Acid SCHEMBL5071235 0.97 KDM4E (0.68) KDM4EMAPTALOX15MAPK1RECQL
Bromide SCHEMBL20553882 0.97 KDM4E (0.64) KDM4EMAPTALOX15MAPK1RECQL
Hydrochloric Acid SCHEMBL30964291 0.97 KDM4E (0.68) KDM4EMAPTALOX15MAPK1RECQL
Bromide SCHEMBL210866 0.97 KDM4E (0.64) KDM4EMAPTALOX15MAPK1RECQL
Tromethamine SCHEMBL952901 0.85 KDM4E (0.52) KDM4EMAPTALOX15MAPK1RECQL
Dihydrocaffeic Acid SCHEMBL15520737 0.81 KDM4E (0.56) KDM4EMAPTALOX15MAPK1RECQL
Dopamine SCHEMBL496657 0.80 KDM4E (1.00) KDM4EMAPTALOX15MAPK1RECQL
Dopamine SCHEMBL8505 0.80 KDM4E (1.00) KDM4EMAPTALOX15MAPK1RECQL
SCHEMBL22499985 0.80 BACE1 (0.52) KDM4EMAPTALOX15MAPK1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 947 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435280-B2 Crude oil demulsifier compositions and uses thereof ECOLAB USA INC. (US) 2025-10-07 US claimed
EP-3911795-B1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2025-10-01 EP claimed
EP-4453566-A2 CRITICALLY-LOCKED MECHANICAL METAMATERIAL FOR HYPER-RESPONSIVE MOLECULAR PROFILING National University of Singapore (SG) 2024-10-30 EP claimed
US-20240299337-A1 Prevention and Treatment of Viral Infections BARANOWITZ STEVEN (US) 2024-09-12 US claimed
CN-114207075-B Functional graphene materials as adhesives and sealants 卡内基梅隆大学 2024-07-05 CN claimed
US-12018202-B2 Functional graphenic materials for use as adhesives and sealants CARNEGIE MELLON UNIVERSITY 2024-06-25 US claimed
EP-4381038-A1 SUGAR/GLUCONOAMIDE ALKOXYLATE COMPOSITIONS AND USES THEREOF Ecolab USA Inc. (US) 2024-06-12 EP claimed
EP-4076733-B1 PEROVSKITE SOLAR CELL PROVIDED WITH AN ADSORBENT MATERIAL FOR ADSORBING TOXIC MATERIALS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2024-02-07 EP claimed
CN-117100901-A Photoinitiated biological tissue adhesive, gel sheet, preparation method and application 艾弈医疗科技(上海)有限公司 2023-11-24 CN claimed
WO-2023121567-A2 CRITICALLY-LOCKED MECHANICAL METAMATERIAL FOR HYPER-RESPONSIVE MOLECULAR PROFILING NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-06-29 WO claimed
CN-1306205-A Process for preparing ammonia cation free-radical modified single-layer membrane of carbon electrode CHANGCHUN APPLIED CHEMISTRY (CN) 2001-08-01 CN claimed
US-6265611-B1 USE AS ANTIOXIDANTS OR FREE-RADICAL SCAVENGERS IN COSMETICS AND PHARMACEUTICALS AND FOODS HAARMANN & REIMER GMBH (DE) 2001-07-24 US claimed
US-6117365-A N-(3,4-DIHYDROXYBENZYL)-3,5-DIMETHOXY-4-HYDROXY-E-CINNAMIDE, FOR EXAMPLE; USE AS ANTIOXIDANTS OR AS FREE-RADICAL SCAVENGERS, IN PARTICULAR IN THE COSMETIC OR DERMATOLOGICAL FIELDS, AND IN FOODS HAARMANN & REIMER GMBH (DE) 2000-09-12 US claimed
EP-1029849-A1 Hydroxymandelamides of phenolic amines HAARMANN & REIMER GMBH (DE) 2000-08-23 EP claimed
EP-0900781-A2 Phenolic acid amides of hydroxy substituted benzylamines HAARMANN & REIMER GMBH (DE) 1999-03-10 EP claimed
US-5538752-A APPLYING PRESERVATIVES TO PLANTS TO INHIBIT DECAY REGENTS OF THE UNIV. OF MINNESOTA (US) 1996-07-23 US claimed
US-4609544-A Process for tanning the skin REPLIGEN CORPORATION (US) 1986-09-02 US claimed
US-4515773-A Skin tanning composition and method REPLIGEN CORPORATION (US) 1985-05-07 US claimed
EP-0035161-B1 CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS Dr. Karl Thomae GmbH (DE) 1983-11-23 EP claimed
US-4370327-A Cephalosporins and pharmaceutical compositions BOEHRINGER INGELHEIM GMBH (DE) 1983-01-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240299337-A1 Prevention and Treatment of Viral Infections MAVS, HAVCR2, NEU4 KDM4E 4603/4885MAPT 2633/4885ALOX15 1065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.