Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dopamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.95 |
| ▸ | MAPT | P10636 | 3/20 | 0.95 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.95 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.95 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.95 |
| ▸ | DRD2 | P14416 | 2/20 | 0.95 |
| ▸ | DRD1 | P21728 | 2/20 | 0.95 |
| ▸ | DRD4 | P21917 | 2/20 | 0.95 |
| ▸ | DRD5 | P21918 | 2/20 | 0.95 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.95 |
| ▸ | DRD3 | P35462 | 2/20 | 0.95 |
| ▸ | RECQL | P46063 | 2/20 | 0.95 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.95 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.95 |
| ▸ | APEX1 | P27695 | 2/20 | 0.95 |
| ▸ | TP53 | P04637 | 1/20 | 0.95 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.95 |
| ▸ | HTR1A | P08908 | 1/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dopamine SCHEMBL30960386 | 1.00 | KDM4E (0.95) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL9166387 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL8505 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL16685137 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL30379944 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL29362033 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL29375089 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL18159501 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL496657 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL23704750 | 0.95 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118022696-B | Boron adsorption resin and preparation method thereof, and method for extracting boron from salt lake brine | 江苏海普功能材料有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-118022696-A | Boron adsorption resin and preparation method thereof, and method for extracting boron from salt lake brine | 江苏海普功能材料有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-111892507-B | Synthesis method of dopamine hydrochloride | 山东达冠医药科技有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-111925293-B | Preparation method of dopamine hydrochloride | 山东达冠医药科技有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-114605275-A | Novel synthesis method of dopamine without bromine hydrochloride | 上海现代哈森（商丘）药业有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-114276570-A | Glucose limiting membrane liquid and preparation method and application thereof | 江苏鱼跃凯立特生物科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-114230683-A | Zwitterionic polymer and preparation method and application thereof | 江苏鱼跃凯立特生物科技有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-110575839-B | M2C/carbon nanosheet composite material and preparation method and application thereof | 北京纳米能源与系统研究所 | 2022-01-25 | — | — | CN | claimed |
| CN-111925293-A | Preparation method of dopamine hydrochloride | 山东达冠医药科技有限公司 | 2020-11-13 | — | — | CN | claimed |
| CN-111892507-A | Synthesis method of high-purity dopamine hydrochloride | 山东达冠医药科技有限公司 | 2020-11-06 | — | — | CN | claimed |
| CN-110575839-A | M2C/carbon nanosheet composite material and preparation method and application thereof | 北京纳米能源与系统研究所 | 2019-12-17 | — | — | CN | claimed |
| CN-105777573-B | The preparation method of N coumaric acyl dopamines | 海门德思行药业科技有限公司 | 2018-01-16 | — | — | CN | claimed |
| CN-107522827-A | A kind of photocuring 3D printing photosensitive resin and its preparation method and application | 杨军 | 2017-12-29 | — | — | CN | claimed |
| CN-105777573-A | Preparation method of N-coumaroyldopamine | 海门德思行药业科技有限公司 | 2016-07-20 | — | — | CN | claimed |
| US-7846628-B2 | Hole blocking layer containing photoconductors | XEROX CORPORATION (US) | 2010-12-07 | — | — | US | claimed |
| US-20080311497-A1 | HOLE BLOCKING LAYER CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2008-12-18 | — | — | US | claimed |
| US-20260091004-A1 | PHARMACEUTICAL INJECTABLE SOLUTION COMPRISING DOPAMINE | INBRAIN PHARMA (FR) | 2026-04-02 | — | — | US | disclosed |
| EP-4586995-A1 | PHARMACEUTICAL INJECTABLE SOLUTION COMPRISING DOPAMINE | InBrain Pharma (FR) | 2025-07-23 | — | — | EP | disclosed |
| WO-1983003968-A1 | BRAIN-SPECIFIC DRUG DELIVERY | UNIVERSITY OF FLORIDA (US) | 1983-11-24 | — | — | WO | disclosed |
| US-4033997-A | Preparation of dopamine derivatives | ABBOTT LABORATORIES (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260091004-A1 | PHARMACEUTICAL INJECTABLE SOLUTION COMPRISING DOPAMINE | PARK7, SNCA, SLC6A3 | KDM4E 3224/4885MAPT 578/4885MAPK1 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.