Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21008326 | 0.79 | NPC1 (0.47) | ALDH1A1MAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL18677661 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MAPTGAAHTTSMN1; SMN2 | |
| SCHEMBL19412850 | 0.75 | MAPT (0.49) | ALDH1A1MAPTGAASMN1; SMN2CYP1A2 | |
| SCHEMBL8059098 | 0.72 | ALDH1A1 (0.78) | ALDH1A1MAPTGAAHTTSMN1; SMN2 | |
| SCHEMBL11668331 | 0.72 | ALDH1A1 (0.63) | ALDH1A1MAPTGAAHTTSMN1; SMN2 | |
| SCHEMBL22965576 | 0.72 | TGM2 (0.38) | ALDH1A1MAPTGAAHTTCYP1A2 | |
| SCHEMBL12655119 | 0.70 | KMT2A (0.78) | ALDH1A1MAPTGAAHTTSMN1; SMN2 | |
| SCHEMBL25003833 | 0.70 | ALDH1A1 (0.42) | ALDH1A1MAPTGAAHTTSMN1; SMN2 | |
| Phenyl Phenylcarbamate SCHEMBL272994 | 0.68 | ALDH1A1 (0.76) | ALDH1A1MAPTGAAHTTSMN1; SMN2 | |
| SCHEMBL29265480 | 0.67 | ALDH1A1 (0.58) | ALDH1A1MAPTGAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711131-B2 | High-strength rubber composition comprising an aromatic polyphenol derivative | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2020-07-14 | — | — | US | disclosed |
| US-20190177532-A1 | HIGH-STRENGTH RUBBER COMPOSITION COMPRISING AN AROMATIC POLYPHENOL DERIVATIVE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2019-06-13 | — | — | US | disclosed |