Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | PLAU | P00749 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26739608 | 0.83 | MAPT (0.43) | GAAALDH1A1MEN1LMNAMAPT | |
| SCHEMBL12363682 | 0.81 | TSHR (0.42) | GAACNR1P2RX3FFAR4HPGD | |
| SCHEMBL8312905 | 0.78 | ALDH1A1 (0.42) | GAACNR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL15934238 | 0.77 | PLAU (0.36) | GAAPLAUF2PLGPLAT | |
| SCHEMBL28656367 | 0.77 | HTR6 (0.34) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL16483015 | 0.74 | FFAR4 (0.37) | GAACNR1P2RX3FFAR4HPGD | |
| SCHEMBL19088278 | 0.74 | ALDH1A1 (0.48) | GAAFFAR4ALDH1A1KMT2ANPSR1 | |
| SCHEMBL3783747 | 0.73 | TSHR (0.41) | GAAALDH1A1MEN1LMNAMAPT | |
| SCHEMBL463751 | 0.73 | TSHR (0.50) | GAAALDH1A1MEN1LMNAMAPT | |
| SCHEMBL16395793 | 0.73 | KCNK3 (0.38) | FFAR4PLAUF2PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191445-B1 | CYCLOBUTANE CONTAINING CARBOXYLIC ACID GPR120 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2019-06-12 | — | — | EP | disclosed |