Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12127949 | 0.81 | ALDH1A1 (0.38) | GLARORCRORBLMNANPC1 | |
| SCHEMBL387559 | 0.81 | ALDH1A1 (0.38) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL16271800 | 0.78 | ALDH1A1 (0.42) | HTR6LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15934238 | 0.77 | PLAU (0.36) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL21087012 | 0.77 | GAA (0.36) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL20523542 | 0.76 | RIPK2 (0.41) | HTR6PLAUF2PLGPLAT | |
| SCHEMBL15095752 | 0.74 | FFAR4 (0.37) | RORCRORBLMNANPC1NFKB1 | |
| SCHEMBL12178544 | 0.74 | ALDH1A1 (0.48) | RORCRORBLMNARAB9AALDH1A1 | |
| SCHEMBL1109742 | 0.73 | HTR6 (0.44) | HTR6 | |
| SCHEMBL24269911 | 0.73 | RORC (0.30) | RORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412113-B | Amino oxazinamides | 豪夫迈·罗氏有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-113412113-A | Aminooxazine amides | 豪夫迈·罗氏有限公司 | 2021-09-17 | — | — | CN | disclosed |