SCHEMBL2108764

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL991518	0.82	MAPK1 (0.46)	MAPK1SIRT6BACE1KDM4EL3MBTL1
	SCHEMBL936961	0.82	SIRT6 (0.42)	MAPK1SIRT6BACE1KDM4EL3MBTL1
	Hydrochloric Acid SCHEMBL17668830	0.81	SIRT6 (0.41)	MAPK1SIRT6BACE1KDM4EL3MBTL1
	SCHEMBL17668828	0.81	BACE1 (0.41)	SIRT6BACE1ACACB
	SCHEMBL1585317	0.81	MAPK1 (0.45)	MAPK1SIRT6BACE1KDM4EL3MBTL1
	SCHEMBL10329867	0.80	MAPK1 (0.47)	MAPK1SIRT6KDM4EL3MBTL1LCK
	SCHEMBL2107109	0.79	MAPK1 (0.44)	MAPK1SIRT6BACE1KDM4EL3MBTL1
	SCHEMBL2108636	0.78	L3MBTL1 (0.48)	MAPK1SIRT6BACE1L3MBTL1LMNA
	SCHEMBL31132803	0.78	L3MBTL1 (0.48)	MAPK1SIRT6BACE1L3MBTL1LMNA
	SCHEMBL13524601	0.78	SIRT6 (0.67)	MAPK1SIRT6KDM4EL3MBTL1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.