SCHEMBL991518

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2107109	0.87	MAPK1 (0.44)	MAPK1SIRT6KDM4EL3MBTL1BACE1
	SCHEMBL10329867	0.84	MAPK1 (0.47)	MAPK1SIRT6KDM4EL3MBTL1LCK
	SCHEMBL23538019	0.83	POLB (0.45)	SIRT6KDM4EL3MBTL1POLBGABRP
	SCHEMBL2108764	0.82	MAPK1 (0.42)	MAPK1SIRT6KDM4EL3MBTL1BACE1
	SCHEMBL31132803	0.82	L3MBTL1 (0.48)	MAPK1SIRT6L3MBTL1BACE1BACE2
	SCHEMBL2108636	0.82	L3MBTL1 (0.48)	MAPK1SIRT6L3MBTL1BACE1BACE2
	SCHEMBL13524601	0.82	SIRT6 (0.67)	MAPK1SIRT6KDM4EL3MBTL1LCK
	SCHEMBL20685032	0.81	BACE1 (0.43)	SIRT6BACE1BACE2CYP2D6CYP2C9
	SCHEMBL68869	0.81	MAPK1 (0.63)	MAPK1SIRT6KDM4EL3MBTL1LCK
	SCHEMBL18662032	0.81	MAPK1 (0.41)	MAPK1SIRT6KDM4EL3MBTL1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.