Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18047282 | 0.80 | ALDH1A1 (0.58) | ALDH1A1EPHX1KMT2AMEN1FKBP1A | |
| SCHEMBL25220996 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL3988453 | 0.78 | POLB (0.48) | ALDH1A1EPHX1KDM4EEPHX2LMNA | |
| SCHEMBL3791323 | 0.77 | ALDH1A1 (0.45) | ALDH1A1EPHX1KMT2AMEN1FKBP1A | |
| SCHEMBL1414262 | 0.77 | ALDH1A1 (0.60) | ALDH1A1EPHX1KMT2AMEN1TAAR1 | |
| SCHEMBL22416691 | 0.77 | ALDH1A1 (0.60) | ALDH1A1EPHX1KMT2AMEN1TAAR1 | |
| SCHEMBL19024739 | 0.76 | EPHX1 (0.53) | ALDH1A1EPHX1KMT2AMEN1GAA | |
| SCHEMBL1203989 | 0.76 | POLB (0.46) | ALDH1A1FKBP1AKDM4EEPHX2LMNA | |
| SCHEMBL20034839 | 0.76 | FKBP1A (0.43) | ALDH1A1FKBP1ASMN1; SMN2GAA | |
| SCHEMBL5981838 | 0.76 | ENPP2 (0.46) | ALDH1A1EPHX1KMT2AMEN1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |