Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22323279 | 0.83 | EPHX2 (0.40) | MLYCDEPHX2EPHX1CTSK | |
| SCHEMBL21089309 | 0.79 | CTSK (0.34) | MLYCDCTSKCYP11B1CYP11B2GPR119 | |
| SCHEMBL22323198 | 0.77 | EPHX1 (0.44) | MLYCDEPHX2EPHX1 | |
| SCHEMBL3452059 | 0.77 | EPHX1 (0.48) | MLYCDEPHX2EPHX1 | |
| SCHEMBL18183061 | 0.77 | KDM1A (0.50) | — | |
| SCHEMBL3725473 | 0.76 | EPHX1 (0.50) | MLYCDEPHX2EPHX1 | |
| SCHEMBL6351612 | 0.74 | EPHX2 (0.45) | MLYCDEPHX2EPHX1 | |
| SCHEMBL21089246 | 0.72 | CACNA1H (0.33) | CYP11B1CYP11B2GPR119 | |
| SCHEMBL15507268 | 0.69 | GPR119 (0.55) | GPR119 | |
| SCHEMBL7380787 | 0.67 | EPHX1 (0.38) | EPHX2CA14EPHX1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |