Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25634890 | 0.87 | EPHX2 (0.34) | GPR119MLYCD | |
| SCHEMBL21089281 | 0.79 | MLYCD (0.36) | CTSKCYP11B1CYP11B2GPR119MLYCD | |
| SCHEMBL21089310 | 0.79 | EPHX2 (0.33) | MLYCD | |
| SCHEMBL18183125 | 0.76 | KDM1A (0.38) | — | |
| SCHEMBL21089246 | 0.73 | CACNA1H (0.33) | CYP11B1CYP11B2GPR119 | |
| SCHEMBL15507268 | 0.70 | GPR119 (0.55) | GPR119 | |
| SCHEMBL13495422 | 0.69 | CTSK (0.35) | CTSKCYP11B1CYP11B2 | |
| SCHEMBL7585222 | 0.69 | BTK (0.41) | CTSK | |
| SCHEMBL7585234 | 0.69 | BTK (0.41) | CTSK | |
| SCHEMBL17271531 | 0.67 | RECQL (0.45) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |