Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25634890 | 0.91 | EPHX2 (0.34) | EPHX2KMT2AMEN1LSSMLYCD | |
| SCHEMBL7585222 | 0.81 | BTK (0.41) | EPHX2KDM1AMAOBKMT2AMEN1 | |
| SCHEMBL7585234 | 0.81 | BTK (0.41) | EPHX2KDM1AMAOBKMT2AMEN1 | |
| SCHEMBL21089309 | 0.79 | CTSK (0.34) | MLYCD | |
| SCHEMBL7587089 | 0.73 | EPHX2 (0.40) | EPHX2KDM1AMAOBKMT2AEPHX1 | |
| SCHEMBL7587093 | 0.73 | EPHX2 (0.40) | EPHX2KDM1AMAOBKMT2AEPHX1 | |
| SCHEMBL10102977 | 0.72 | BTK (0.43) | KDM1AMAOBKMT2AEPHX1ALDH1A1 | |
| SCHEMBL17271531 | 0.72 | RECQL (0.45) | EPHX1ALDH1A1 | |
| SCHEMBL1495989 | 0.71 | EPHX1 (0.49) | MAOBKMT2AMEN1EPHX1ALDH1A1 | |
| SCHEMBL29951969 | 0.69 | PHF8 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |