Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 3/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 10/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188510 | 0.90 | ALDH1A1 (0.46) | PHF8KDM2AKDM4CKDM5AKDM4A | |
| SCHEMBL17406690 | 0.87 | LMNA (0.46) | SLC22A6TSHRALDH1A1 | |
| SCHEMBL28409566 | 0.85 | TSHR (0.48) | PHF8KDM2AKDM7ASLC22A6KDM4C | |
| Hydrochloric Acid SCHEMBL17275903 | 0.85 | ITGB3 (0.42) | KDM4CTSHRKDM4A | |
| SCHEMBL27952219 | 0.84 | LSS (0.35) | — | |
| SCHEMBL15719057 | 0.82 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL27775197 | 0.81 | LMNA (0.39) | ALDH1A1 | |
| SCHEMBL26730971 | 0.81 | ACHE (0.41) | PHF8KDM2ATSHRKDM6BKDM5C | |
| SCHEMBL2676656 | 0.78 | ALDH1A1 (0.44) | PHF8KDM2ASLC22A6KDM4CKDM5A | |
| SCHEMBL1513993 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |