SCHEMBL21089328

SCHEMBL21089328

CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C(F)C1O

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.57
P2RY14 Q15391 5/20 0.52
SLC28A1 O00337 1/20 0.51
SLC28A2 O43868 1/20 0.51
SLC29A1 Q99808 1/20 0.51
SLC28A3 Q9HAS3 1/20 0.51
P2RY6 Q15077 8/20 0.51
P2RY2 P41231 11/20 0.50
P2RY4 P51582 5/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19861744 1.00 DUT (0.57) DUTP2RY14SLC28A1SLC28A2SLC29A1
SCHEMBL10521044 1.00 DUT (0.57) DUTP2RY14SLC28A1SLC28A2SLC29A1
SCHEMBL9218570 0.90 SLC28A1 (0.63) DUTP2RY14SLC28A1SLC28A2SLC29A1
SCHEMBL21078688 0.90 SLC28A1 (0.63) DUTP2RY14SLC28A1SLC28A2SLC29A1
SCHEMBL2762704 0.90 SLC28A1 (0.63) DUTP2RY14SLC28A1SLC28A2SLC29A1
SCHEMBL6060488 0.90 SLC28A1 (0.63) DUTP2RY14SLC28A1SLC28A2SLC29A1
SCHEMBL15866629 0.88 DUT (0.58) DUTP2RY14SLC28A1SLC28A2SLC29A1
SCHEMBL8909630 0.88 DUT (0.57) DUTP2RY14SLC28A1SLC28A2SLC29A1
SCHEMBL25399050 0.87 DUT (0.56) DUTP2RY14SLC28A1SLC28A2SLC29A1
SCHEMBL24781265 0.87 DUT (0.56) DUTP2RY14SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037586-B2 4′-phosphate analogs and oligonucleotides comprising the same DICERNA PHARMACEUTICALS, INC. (US) 2024-07-16 US disclosed
WO-2023183569-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2023-09-28 WO disclosed
US-20230064031-A1 4'-PHOSPHATE ANALOGS AND OLIGONUCLEOTIDES COMPRISING THE SAME NOVO NORDISK A/S (DK) 2023-03-02 US disclosed
US-20190177729-A1 4'-PHOSPHATE ANALOGS AND OLIGONUCLEOTIDES COMPRISING THE SAME NOVO NORDISK A/S (DK) 2019-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230064031-A1 4'-PHOSPHATE ANALOGS AND OLIGONUCLEOTIDES COMPRISING THE SAME RNGTT, DERA, MTAP DUT 9/4885P2RY14 1796/4885SLC28A1 564/4885
US-12037586-B2 4′-phosphate analogs and oligonucleotides comprising the same RNGTT, DERA, MTAP DUT 8/4885P2RY14 1827/4885SLC28A1 566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.