SCHEMBL9218570

SCHEMBL9218570

CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.63
SLC28A2 O43868 1/20 0.63
SLC29A1 Q99808 1/20 0.63
SLC28A3 Q9HAS3 1/20 0.63
P2RY6 Q15077 9/20 0.62
P2RY2 P41231 11/20 0.61
P2RY4 P51582 6/20 0.61
P2RY14 Q15391 6/20 0.61
DUT P33316 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21078688 1.00 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2762704 1.00 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL6060488 1.00 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL15866629 0.91 DUT (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL21089328 0.90 DUT (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL10521044 0.90 DUT (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8909630 0.90 DUT (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL19861744 0.90 DUT (0.57) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL24782135 0.89 DUT (0.56) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL21089723 0.89 DUT (0.56) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240158431-A1 COMPOSITIONS AND COMPOUNDS FOR CO-DELIVERY OF URIDINE AND KETOLEUCINE WELLSTAT THERAPEUTICS CORPORATION 2024-05-16 US disclosed
CN-117529326-A Compositions and compounds for co-delivery of uridine and ketoleucine 制药五有限责任公司 2024-02-06 CN disclosed
EP-4294405-A1 COMPOSITIONS AND COMPOUNDS FOR CO-DELIVERY OF URIDINE AND KETOLEUCINE Pharma Cinq, LLC (US) 2023-12-27 EP disclosed
US-11548910-B2 Oligonucleotide production method NISSAN CHEMICAL CORPORATION (JP) 2023-01-10 US disclosed
CN-109641931-B Method for synthesizing ribonucleic acid H-phosphate monomer and oligonucleotide synthesis using the same 基因设计有限公司 2022-10-18 CN disclosed
WO-2022177740-A1 COMPOSITIONS AND COMPOUNDS FOR CO-DELIVERY OF URIDINE AND KETOLEUCINE WELLSTAT THERAPEUTICS CORPORATION (US) 2022-08-25 WO disclosed
US-11174279-B2 Method for synthesizing ribonucleic acid H-phosphonate monomer, and oligonucleotide synthesis in which said monomer is used NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2021-11-16 US disclosed
US-20200331945-A1 METHOD FOR SYNTHESIZING RIBONUCLEIC ACID H-PHOSPHONATE MONOMER, AND OLIGONUCLEOTIDE SYNTHESIS IN WHICH SAID MONOMER IS USED NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2020-10-22 US disclosed
US-20190169223-A1 OLIGONUCLEOTIDE PRODUCTION METHOD NISSAN CHEMICAL CORPORATION (JP) 2019-06-06 US disclosed
EP-3473637-A1 METHOD FOR SYNTHESIZING RIBONUCLEIC ACID H-PHOSPHONATE MONOMER, AND OLIGONUCLEOTIDE SYNTHESIS IN WHICH SAID MONOMER IS USED Genedesign, Inc. (JP) 2019-04-24 EP disclosed
EP-3378869-A1 METHOD FOR PRODUCING OLIGONUCLEOTIDE Nissan Chemical Corporation (JP) 2018-09-26 EP disclosed
US-5455339-A Method for the preparation of 2',3'-dideoxy and 2',3'-dideoxydide-hydro nucleosides UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1995-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548910-B2 Oligonucleotide production method RNGTT, OSGEP, PHAX SLC28A1 601/4885SLC28A2 474/4885SLC29A1 324/4885
US-20200331945-A1 METHOD FOR SYNTHESIZING RIBONUCLEIC ACID H-PHOSPHONATE MONOMER, AND OLIGONUCLEOTIDE SYNTHESIS IN WHICH SAID MONOMER IS USED RNGTT, RNASEL, NSUN3 SLC28A1 1597/4885SLC28A2 1562/4885SLC29A1 551/4885
US-20190169223-A1 OLIGONUCLEOTIDE PRODUCTION METHOD RNGTT, OSGEP, PHAX SLC28A1 601/4885SLC28A2 474/4885SLC29A1 324/4885
US-11174279-B2 Method for synthesizing ribonucleic acid H-phosphonate monomer, and oligonucleotide synthesis in which said monomer is used RNGTT, RNASEL, NSUN3 SLC28A1 1597/4885SLC28A2 1562/4885SLC29A1 551/4885
US-20240158431-A1 COMPOSITIONS AND COMPOUNDS FOR CO-DELIVERY OF URIDINE AND KETOLEUCINE CPT1B, UMPS, CKMT1A; CKMT1B SLC28A1 826/4885SLC28A2 831/4885SLC29A1 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.