Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957354 | 0.82 | RAB9A (0.40) | ALDH1A1L3MBTL1NPSR1RAB9ANPC1 | |
| SCHEMBL957356 | 0.82 | RAB9A (0.40) | ALDH1A1L3MBTL1NPSR1RAB9ANPC1 | |
| SCHEMBL955107 | 0.80 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1NPSR1RAB9ANPC1 | |
| SCHEMBL956459 | 0.80 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1NPSR1RAB9ANPC1 | |
| SCHEMBL955109 | 0.80 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1NPSR1RAB9ANPC1 | |
| SCHEMBL956457 | 0.80 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1NPSR1RAB9ANPC1 | |
| SCHEMBL13304360 | 0.71 | PTPN2 (0.33) | — | |
| SCHEMBL18472141 | 0.68 | EPHX2 (0.41) | ALDH1A1L3MBTL1RAB9ANPC1HPGD | |
| SCHEMBL8333357 | 0.67 | RAB9A (0.51) | ALDH1A1L3MBTL1RAB9ANPC1HPGD | |
| SCHEMBL8333354 | 0.67 | RAB9A (0.51) | ALDH1A1L3MBTL1RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3100723-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |