Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333357 | 1.00 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| Hydroxyl Radical SCHEMBL28161121 | 0.98 | RAB9A (0.50) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| Oxalic Acid SCHEMBL29689200 | 0.94 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL28169566 | 0.86 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL25237838 | 0.84 | MAPT (0.41) | ALDH1A1KDM4EMEN1TP53KMT2A | |
| SCHEMBL27656999 | 0.84 | — | — | |
| SCHEMBL28074921 | 0.82 | RAB9A (0.55) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL293876 | 0.82 | SMN1; SMN2 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL20288910 | 0.81 | RAB9A (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL26699141 | 0.81 | SMN1; SMN2 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580717-A | Solvent-free photo-curing quantum dot ink and application thereof | 致晶科技（北京）有限公司 | 2024-09-03 | — | — | CN | claimed |
| US-20260022092-A1 | PROCESS FOR SOLVENT FREE CONTINUOUS SYNTHESIS OF AMIDES AND PEPTIDES | COUNCIL SCIENT IND RES (IN) | 2026-01-22 | — | — | US | disclosed |
| CN-118580717-A | Solvent-free photo-curing quantum dot ink and application thereof | 致晶科技（北京）有限公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2024013769-A1 | PROCESS FOR SOLVENT FREE CONTINUOUS SYNTHESIS OF AMIDES AND PEPTIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2024-01-18 | — | — | WO | disclosed |
| EP-4194441-A1 | NITROXOLINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022253152-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |
| EP-3613743-B1 | PROCESSES FOR THE PREPARATION OF 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES | INTELLIKINE LLC (US) | 2022-03-16 | — | — | EP | disclosed |
| EP-3441392-B1 | A PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION | INTELLIKINE LLC (US) | 2021-12-15 | — | — | EP | disclosed |
| EP-3811974-A1 | TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS | Infinity Pharmaceuticals, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |
| EP-3555085-B1 | CYCLOPROPYL FUSED THIAZINE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND METHODS OF USE | AMGEN INC (US) | 2020-12-02 | — | — | EP | disclosed |
| US-8080551-B2 | HIV inhibiting pyrimidines derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-12-20 | — | — | US | disclosed |
| US-8026245-B2 | HIV replication inhibiting purine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-09-27 | — | — | US | disclosed |
| WO-2011090062-A1 | PIPERAZINE COMPOUND HAVING A PGDS INHIBITORY EFFECT | 大鵬薬品工業株式会社 (JP) | 2011-07-28 | — | — | WO | disclosed |
| EP-2298761-A1 | HIV inhibiting pyrimidines derivatives | Janssen Pharmaceutica NV (BE) | 2011-03-23 | — | — | EP | disclosed |
| US-20100034810-A1 | PYRIMIDINE DERIVATIVES FOR THE PREVENTION OF HIV INFECTION | JANSSEN-CILAG (FR) | 2010-02-11 | — | — | US | disclosed |
| WO-2009088986-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2009-07-16 | — | — | WO | disclosed |
| WO-2008047883-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-04-24 | — | — | WO | disclosed |
| US-20070021449-A1 | Pyrimidine derivatives for the prevention of hiv infection | HEERES JAN | 2007-01-25 | — | — | US | disclosed |
| WO-1998042657-A9 | SYNTHESIS OF α,β-SUBSTITUTED AMINO AMIDES, ESTERS AND ACIDS | — | 1999-01-28 | — | — | WO | disclosed |
| WO-1998042657-A1 | SYNTHESIS OF α,β-SUBSTITUTED AMINO AMIDES, ESTERS AND ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021449-A1 | Pyrimidine derivatives for the prevention of hiv infection | ADORA2B, CYP1B1, DPYD | RAB9A 2549/4885SMN1; SMN2 3722/4885NPC1 2768/4885 |
| US-20260022092-A1 | PROCESS FOR SOLVENT FREE CONTINUOUS SYNTHESIS OF AMIDES AND PEPTIDES | TNF, VIP, APP | RAB9A 3382/4885SMN1; SMN2 2942/4885NPC1 3329/4885 |
| US-20100034810-A1 | PYRIMIDINE DERIVATIVES FOR THE PREVENTION OF HIV INFECTION | NOX3, CBR3, CBR1 | RAB9A 2882/4885SMN1; SMN2 4522/4885NPC1 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.