Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 3/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 3/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17196388 | 0.85 | PTAFR (0.34) | PTAFRDRD2SIGMAR1TYK2NR1H2 | |
| SCHEMBL17177879 | 0.74 | TYK2 (0.42) | TYK2NR1H2NR1H3 | |
| SCHEMBL18811516 | 0.74 | PTAFR (0.33) | PTAFRDRD2SIGMAR1TYK2 | |
| SCHEMBL21354998 | 0.73 | MAP3K12 (0.43) | TYK2NR1H2NR1H3 | |
| SCHEMBL17173652 | 0.72 | TYK2 (0.34) | TYK2NR1H2NR1H3 | |
| SCHEMBL24587299 | 0.71 | LRRK2 (0.37) | TYK2NR1H2NR1H3 | |
| SCHEMBL21089373 | 0.70 | THRA (0.34) | HDAC6NR1H2NR1H3 | |
| SCHEMBL23564201 | 0.70 | SPHK1 (0.40) | APLNRSPHK1 | |
| SCHEMBL20885627 | 0.69 | TYK2 (0.34) | TYK2 | |
| SCHEMBL17504812 | 0.69 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495360-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | Grünenthal GmbH (DE) | 2019-06-12 | — | — | EP | disclosed |