Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21052432 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2ALPLGAAALPGCRHBP | |
| SCHEMBL21090321 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2ALPLGAAALPGALDH1A1 | |
| SCHEMBL22709486 | 0.68 | SMN1; SMN2 (0.96) | SMN1; SMN2ALPLGAAALPGALDH1A1 | |
| SCHEMBL21090322 | 0.67 | SMN1; SMN2 (0.54) | SMN1; SMN2ALPLGAAALPGALDH1A1 | |
| SCHEMBL22686671 | 0.66 | SMN1; SMN2 (0.52) | SMN1; SMN2ALPLGAAALPGALDH1A1 | |
| SCHEMBL21052523 | 0.66 | CA1 (0.58) | ALDH1A1MAPT | |
| SCHEMBL19992029 | 0.62 | — | — | |
| SCHEMBL626418 | 0.61 | GSK3B (0.46) | GAASIRT2SIRT1ALDH1A1MAPT | |
| Iodide SCHEMBL2495412 | 0.60 | GSK3B (0.45) | GAASIRT2SIRT1ALDH1A1MAPT | |
| SCHEMBL4631943 | 0.59 | PTGER3 (0.42) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720597-B1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES | STICHTING TECHNISCHE WETENSCHAPPEN (NL) | 2023-11-29 | — | — | EP | claimed |
| US-11612877-B2 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-03-28 | — | — | US | claimed |
| US-20200368721-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2020-11-26 | — | — | US | claimed |
| US-12318756-B2 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | UNIVERSITEIT UTRECHT HOLDING B.V. (NL) | 2025-06-03 | — | — | US | disclosed |
| EP-3720597-B1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES | STICHTING TECHNISCHE WETENSCHAPPEN (NL) | 2023-11-29 | — | — | EP | disclosed |
| EP-3720597-B1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES | STICHTING TECHNISCHE WETENSCHAPPEN (NL) | 2023-11-29 | — | — | EP | disclosed |
| US-20230201799-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-06-29 | — | — | US | disclosed |
| US-20230201799-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-06-29 | — | — | US | disclosed |
| US-20230201799-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-06-29 | — | — | US | disclosed |
| US-11612877-B2 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-03-28 | — | — | US | disclosed |
| US-20200368721-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2020-11-26 | — | — | US | disclosed |
| US-20200368721-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2020-11-26 | — | — | US | disclosed |
| WO-2019110557-A1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2019-06-13 | — | — | WO | disclosed |