Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21090322 | 0.94 | SMN1; SMN2 (0.54) | SMN1; SMN2ALPLGAAALPGALDH1A1 | |
| SCHEMBL21090321 | 0.94 | SMN1; SMN2 (0.54) | SMN1; SMN2ALPLGAAALPGALK | |
| SCHEMBL22709486 | 0.71 | SMN1; SMN2 (0.96) | SMN1; SMN2ALPLGAAALPGALDH1A1 | |
| SCHEMBL21052525 | 0.68 | CA1 (0.55) | ALDH1A1 | |
| SCHEMBL25699110 | 0.66 | ALK (0.33) | ALKALDH1A1MAPT | |
| SCHEMBL21090323 | 0.66 | SMN1; SMN2 (0.50) | SMN1; SMN2ALPLGAAALPGALDH1A1 | |
| SCHEMBL25698912 | 0.65 | CA1 (0.42) | ALKALDH1A1MAPT | |
| SCHEMBL21052432 | 0.64 | SMN1; SMN2 (0.51) | SMN1; SMN2ALPLGAAALPGALDH1A1 | |
| SCHEMBL11519236 | 0.64 | PPOX (0.50) | ALDH1A1MAPT | |
| SCHEMBL17016640 | 0.62 | ALDH1A1 (0.34) | ALKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200368721-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2020-11-26 | — | — | US | claimed |