Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21019024 | 0.85 | L3MBTL1 (0.38) | L3MBTL1MAPTTDP1POLBKDM4E | |
| SCHEMBL22624549 | 0.79 | TSHR (0.55) | L3MBTL1MAPTTDP1POLBKDM4E | |
| SCHEMBL4089395 | 0.79 | TSHR (0.55) | L3MBTL1MAPTTDP1POLBKDM4E | |
| SCHEMBL23341753 | 0.79 | TSHR (0.55) | L3MBTL1MAPTTDP1POLBKDM4E | |
| SCHEMBL20225784 | 0.77 | TAAR1 (0.47) | L3MBTL1MAPTTDP1POLBKDM4E | |
| SCHEMBL24239796 | 0.75 | POLB (0.43) | L3MBTL1MAPTTDP1POLBKDM4E | |
| SCHEMBL25700242 | 0.74 | L3MBTL1 (0.41) | L3MBTL1MAPTTDP1POLBKDM4E | |
| SCHEMBL28786027 | 0.74 | L3MBTL1 (0.41) | L3MBTL1MAPTTDP1POLBKDM4E | |
| SCHEMBL2737240 | 0.73 | L3MBTL1 (0.55) | L3MBTL1MAPTTDP1POLBKDM4E | |
| SCHEMBL23766332 | 0.73 | POLB (0.36) | L3MBTL1MAPTTDP1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113227-A1 | PRODRUGS ACTIVATED BY REDUCTION IN THE CYTOSOL | YALE UNIVERSITY (US) | 2019-06-13 | — | — | WO | disclosed |