Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089395 | 0.82 | TSHR (0.55) | L3MBTL1MAPTTDP1KDM4EUSP2 | |
| SCHEMBL22624549 | 0.82 | TSHR (0.55) | L3MBTL1MAPTTDP1KDM4EUSP2 | |
| SCHEMBL23341753 | 0.82 | TSHR (0.55) | L3MBTL1MAPTTDP1KDM4EUSP2 | |
| SCHEMBL21019024 | 0.80 | L3MBTL1 (0.38) | TAAR1L3MBTL1MAPTTDP1KDM4E | |
| SCHEMBL21092206 | 0.77 | L3MBTL1 (0.39) | TAAR1L3MBTL1MAPTTDP1KDM4E | |
| SCHEMBL16918922 | 0.77 | CYP2D6 (0.42) | L3MBTL1MAPTTDP1KDM4EUSP2 | |
| SCHEMBL2737240 | 0.76 | L3MBTL1 (0.55) | HTR2CHTR2BL3MBTL1MAPTTDP1 | |
| SCHEMBL23766332 | 0.76 | POLB (0.36) | TAAR1L3MBTL1MAPTTDP1KDM4E | |
| SCHEMBL25442165 | 0.74 | HTT (0.38) | L3MBTL1MAPTTDP1KDM4EUSP2 | |
| SCHEMBL23075059 | 0.74 | TAAR1 (0.54) | TAAR1HTR2AHTR2CHTR2BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180159051-A1 | EMITTERS BASED ON OCTAHEDRAL METAL COMPLEXES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180159051-A1 | EMITTERS BASED ON OCTAHEDRAL METAL COMPLEXES | POLR1G, ITPA, ERCC5 | TAAR1 2142/4885HTR2A 3967/4885HTR2C 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.