Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685019 | 0.82 | TSHR (0.45) | POLBTSHRKDM4EALDH1A1MAPT | |
| SCHEMBL11800992 | 0.81 | ALDH1A1 (0.43) | POLBTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL21230477 | 0.81 | SOAT1 (0.31) | SOAT1 | |
| SCHEMBL4089395 | 0.81 | TSHR (0.55) | POLBTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL22624549 | 0.81 | TSHR (0.55) | POLBTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL23341753 | 0.81 | TSHR (0.55) | POLBTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL15105377 | 0.77 | TSHR (0.41) | POLBTSHRKDM4EALDH1A1CNR2 | |
| SCHEMBL6686891 | 0.77 | TSHR (0.41) | POLBTSHRHPGDSOAT1 | |
| SCHEMBL6678854 | 0.77 | TSHR (0.43) | TSHRALDH1A1NPSR1CNR2KMT2A | |
| SCHEMBL11800482 | 0.76 | KCNH3 (0.40) | L3MBTL1KDM4EALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925771-B1 | A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES | COUNCIL SCIENT IND RES (IN) | 2021-08-18 | — | — | EP | disclosed |