Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.62 |
| ▸ | RELA | Q04206 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939891 | 0.89 | KDM4E (0.58) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL28868336 | 0.84 | MAPT (0.68) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL13799598 | 0.80 | LDHA (0.51) | SMN1; SMN2MAPTHPGDMEN1KMT2A | |
| SCHEMBL74053 | 0.79 | RAB9A (0.68) | SMN1; SMN2KDM4ELMNAMAPTHPGD | |
| Cicloprofen SCHEMBL11060470 | 0.78 | PTGS2 (0.46) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL121572 | 0.77 | KDM4E (1.00) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL27682548 | 0.76 | KDM4E (0.43) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL121577 | 0.76 | KDM4E (0.81) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL12565259 | 0.75 | RAB9A (0.71) | SMN1; SMN2KDM4EMAPTGAAGLA | |
| SCHEMBL4132162 | 0.75 | DYRK1A (0.63) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| EP-0017543-B1 | BENZOTHIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USES | Albert ROLLAND S.A. Société dite (FR) | 1983-09-28 | — | — | EP | claimed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| US-11191719-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2021-12-07 | — | — | US | disclosed |
| US-10463611-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2019-11-05 | — | — | US | disclosed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-20140154313-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2014-06-05 | — | — | US | disclosed |
| EP-2717860-A1 | CONTROLLED ABSORPTION WATER-SOLUBLE PHARMACEUTICALLY ACTIVE ORGANIC COMPOUND FORMULATION FOR ONCE-DAILY ADMINISTRATION | STI Pharma, LLC (US) | 2014-04-16 | — | — | EP | disclosed |
| WO-1996039377-A1 | FACE-TO-FACE/FACE-TO-EDGE INTERACTIVE CHIRAL SELECTORS AND RELATED APPARATUSES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-12-12 | — | — | WO | disclosed |
| US-5484530-A | CARBOXYLIC ACIDS AND ENANTIOMORPHS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-01-16 | — | — | US | disclosed |
| US-5387338-A | An optical isomer separators | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| US-5256293-A | Immobilizing enantiomer on support effective for use in chromatographic separation | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-10-26 | — | — | US | disclosed |
| WO-1993006080-A1 | SEPARATION OF ENANTIOMERS OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND CHIRAL SELECTOR THEREFOR | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-04-01 | — | — | WO | disclosed |
| US-5028603-A | Platelet-Activating Factor Antagonist; Useful In Treatment Of Inflammatory Diseases, Allergic Diseases, Asthma, Respiratory System Disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0316456-A1 | ESTER-SUBSTITUTED THIENOTRIAZOLODIAZEPINE COMPOUNDS AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |