Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21094977 | 1.00 | ADRA2C (0.67) | ADRA2CHTR2ASLC6A4SLC6A2HTR2B | |
| SCHEMBL21094973 | 1.00 | ADRA2C (0.67) | ADRA2CHTR2ASLC6A4SLC6A2HTR2B | |
| Hydrochloric Acid SCHEMBL27431798 | 0.89 | ADRA2C (0.77) | ADRA2CHTR2ASLC6A4SLC6A2HTR2B | |
| SCHEMBL21095168 | 0.88 | ADRA2C (0.63) | ADRA2CHTR2ASLC6A4SLC6A2HTR2B | |
| SCHEMBL9068239 | 0.88 | ADRA2C (0.63) | ADRA2CHTR2ASLC6A4SLC6A2HTR2B | |
| SCHEMBL21095173 | 0.88 | ADRA2C (0.63) | ADRA2CHTR2ASLC6A4SLC6A2HTR2B | |
| Hydrochloric Acid SCHEMBL8702425 | 0.87 | ADRA2C (0.61) | ADRA2CHTR2ASLC6A4SLC6A2HTR2B | |
| Hydrochloric Acid SCHEMBL8702658 | 0.87 | ADRA2C (0.61) | ADRA2CHTR2ASLC6A4SLC6A2HTR2B | |
| Hydrochloric Acid SCHEMBL8702416 | 0.87 | ADRA2C (0.61) | ADRA2CHTR2ASLC6A4SLC6A2HTR2B | |
| Hydrochloric Acid SCHEMBL8706186 | 0.87 | SLC6A4 (0.63) | ADRA2CHTR2ASLC6A4SLC6A2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228508-A1 | COMPOSITIONS AND METHODS THEREOF | Exciva GmbH | 2021-07-29 | — | — | US | disclosed |
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | VEPACHEDU SREENIVASARAO (US) | 2020-08-20 | — | — | US | disclosed |
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-05 | — | — | US | disclosed |
| US-20190183885-A1 | COMPOSITIONS AND METHODS THEREOF | EXCIVA (UG) (haftungsbeschränkt) (DE) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2A, HTR2C, CYP3A43 | ADRA2C 18/4885HTR2A 1/4885SLC6A4 68/4885 |
| US-20210228508-A1 | COMPOSITIONS AND METHODS THEREOF | CYP21A2, CYP2C19, CYP2F1 | ADRA2C 464/4885HTR2A 1705/4885SLC6A4 601/4885 |
| US-20190183885-A1 | COMPOSITIONS AND METHODS THEREOF | CYP21A2, CYP11B2, CYP2D6 | ADRA2C 198/4885HTR2A 2171/4885SLC6A4 757/4885 |
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2C, HTR2A, HTR3A | ADRA2C 21/4885HTR2A 2/4885SLC6A4 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.