Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.59 |
| ▸ | HTR1A | P08908 | 4/20 | 0.59 |
| ▸ | DRD2 | P14416 | 4/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21095600 | 1.00 | ABCB1 (0.59) | ABCB1HTR1ADRD2CYP2D6HTR2A | |
| SCHEMBL21095171 | 1.00 | ABCB1 (0.59) | ABCB1HTR1ADRD2CYP2D6HTR2A | |
| SCHEMBL23693972 | 0.88 | LTA4H (0.55) | ABCB1HTR1ADRD2CYP2D6HTR2A | |
| SCHEMBL21094971 | 0.88 | LTA4H (0.55) | ABCB1HTR1ADRD2CYP2D6HTR2A | |
| SCHEMBL21094976 | 0.88 | LTA4H (0.55) | ABCB1HTR1ADRD2CYP2D6HTR2A | |
| SCHEMBL27402096 | 0.86 | ABCB1 (0.60) | ABCB1HTR1ADRD2CYP2D6HTR2A | |
| SCHEMBL8703238 | 0.86 | ABCB1 (0.60) | ABCB1HTR1ADRD2 | |
| SCHEMBL8703231 | 0.86 | ABCB1 (0.60) | ABCB1HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8703779 | 0.85 | ABCB1 (0.59) | ABCB1HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8703399 | 0.85 | ABCB1 (0.59) | ABCB1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190183885-A1 | COMPOSITIONS AND METHODS THEREOF | EXCIVA (UG) (haftungsbeschränkt) (DE) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190183885-A1 | COMPOSITIONS AND METHODS THEREOF | CYP21A2, CYP11B2, CYP2D6 | ABCB1 105/4885HTR1A 2704/4885DRD2 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.