SCHEMBL21097396

SCHEMBL21097396

CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H]2O[Si](C(C)(C)C)(C(C)(C)C)OC[C@H]2O[C@H]1n1cnc2c(-c3ccc4cc5ccccc5cc4c3)ncnc21

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DNPH1 O43598 15/20 0.43
▸ STING1 Q86WV6 3/20 0.34
▸ GNMT Q14749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17363530 0.98 DNPH1 (0.45) DNPH1STING1GNMT
SCHEMBL18486321 0.90 DNPH1 (0.40) DNPH1STING1
SCHEMBL16871895 0.90 DNPH1 (0.44) DNPH1STING1
SCHEMBL17363656 0.87 DNPH1 (0.37) DNPH1STING1
SCHEMBL17363867 0.87 DNPH1 (0.37) DNPH1STING1
SCHEMBL17363639 0.86 DNPH1 (0.38) DNPH1
SCHEMBL16871708 0.86 DNPH1 (0.38) DNPH1
SCHEMBL17363633 0.86 DNPH1 (0.35) DNPH1STING1
SCHEMBL16871736 0.86 DNPH1 (0.35) DNPH1STING1
SCHEMBL18486268 0.85 DNPH1 (0.37) DNPH1STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10342819-B2 Oligonucleotide having non-natural nucleotide at 5′-terminal thereof KYOWA HAKKO KIRIN CO., LTD. (JP) 2019-07-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10342819-B2 Oligonucleotide having non-natural nucleotide at 5′-terminal thereof RNGTT, UPF1, NSUN3 DNPH1 2051/4885STING1 1024/4885GNMT 3381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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