Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837217 | 0.84 | GABRP (0.40) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL29040356 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL16419610 | 0.74 | GABRP (0.38) | CHEK1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31573332 | 0.73 | PDXK (0.38) | KDM4EALDH1A1CHEK1GABRPGABRD | |
| SCHEMBL17781631 | 0.73 | KDM4E (0.37) | KDM4EALDH1A1CHEK1GABRPGABRD | |
| SCHEMBL21257301 | 0.68 | NPC1 (0.39) | KDM4EALDH1A1HPGDDPP4LMNA | |
| SCHEMBL21063436 | 0.66 | GABRP (0.36) | CHEK1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2056345 | 0.66 | GABRP (0.36) | CHEK1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL836977 | 0.66 | CHEK1 (0.37) | CHEK1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL20917583 | 0.66 | AR (0.38) | CHEK1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |