SCHEMBL21098425

SCHEMBL21098425

COc1cc(N2CCNCC2C)ncn1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.47
HTR2C P28335 10/20 0.38
GSK3B P49841 4/20 0.38
HTR2A P28223 4/20 0.38
PIM1 P11309 2/20 0.37
PIM3 Q86V86 2/20 0.37
PIM2 Q9P1W9 2/20 0.37
MET P08581 1/20 0.37
ALK Q9UM73 1/20 0.37
CYP17A1 P05093 1/20 0.36
KCNH2 Q12809 1/20 0.36
HTR2B P41595 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26669762 1.00 CYP2C19 (0.47) CYP2C19HTR2CGSK3BHTR2APIM1
SCHEMBL21098430 1.00 CYP2C19 (0.47) CYP2C19HTR2CGSK3BHTR2APIM1
Hydrochloric Acid SCHEMBL30619116 0.99 CYP2C19 (0.46) CYP2C19HTR2CGSK3BHTR2APIM1
SCHEMBL31045848 0.80 HTR2C (0.40) HTR2CGSK3BHTR2APIM1PIM3
SCHEMBL17884822 0.80 MMP2 (0.42) HTR2CGSK3BHTR2APIM1PIM3
SCHEMBL21098718 0.78 ALOX5 (0.48) HTR2CHTR2APIM1PIM3PIM2
SCHEMBL21098721 0.78 ALOX5 (0.48) HTR2CHTR2APIM1PIM3PIM2
SCHEMBL21098921 0.77 HTR2C (0.44) HTR2CGSK3BHTR2APIM1PIM3
SCHEMBL21098920 0.77 HTR2C (0.44) HTR2CGSK3BHTR2APIM1PIM3
SCHEMBL21098363 0.77 GSK3B (0.42) HTR2CGSK3BHTR2ACYP17A1HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3498715-B1 ANTI-HCMV VIRUS COMPOUND MEDSHINE DISCOVERY INC (CN) 2021-06-09 EP disclosed
EP-3498715-A1 ANTI-HCMV VIRUS COMPOUND Medshine Discovery Inc. (CN) 2019-06-19 EP disclosed