Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.40 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17884822 | 0.82 | MMP2 (0.42) | HTR2CGSK3BHTR2AHTR2BPIM1 | |
| SCHEMBL21098425 | 0.80 | CYP2C19 (0.47) | HTR2CGSK3BHTR2AHTR2BPIM1 | |
| SCHEMBL26669762 | 0.80 | CYP2C19 (0.47) | HTR2CGSK3BHTR2AHTR2BPIM1 | |
| SCHEMBL21098430 | 0.80 | CYP2C19 (0.47) | HTR2CGSK3BHTR2AHTR2BPIM1 | |
| Hydrochloric Acid SCHEMBL30619116 | 0.79 | CYP2C19 (0.46) | HTR2CGSK3BHTR2AHTR2BPIM1 | |
| SCHEMBL31087059 | 0.79 | CYP2D6 (0.47) | HTR2CHTR2AHTR2B | |
| SCHEMBL17623269 | 0.76 | HTR2C (0.36) | HTR2CGSK3BHTR2AHTR2BCYP1A2 | |
| SCHEMBL27103013 | 0.75 | RAD52 (0.44) | HTR2CGSK3BHTR2AHTR2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL22836914 | 0.74 | RAD52 (0.46) | HTR2CGSK3BHTR2AHTR2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL30062597 | 0.74 | RAD52 (0.46) | HTR2CGSK3BHTR2AHTR2BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665331-A1 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173219-A1 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-08-22 | — | — | WO | disclosed |