Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 9/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272059 | 1.00 | ADRB1 (0.59) | ADRB1HTR2CHTR6HTR2BHTR2A | |
| SCHEMBL19709299 | 0.86 | ADRB1 (0.60) | ADRB1HTR2CHTR6HTR2BHTR2A | |
| SCHEMBL2005355 | 0.83 | ADRB1 (0.56) | ADRB1HTR2CHTR6HTR2BHTR2A | |
| SCHEMBL23777830 | 0.82 | ADRB1 (0.57) | ADRB1HTR2CHTR6HTR2BHTR2A | |
| SCHEMBL30996886 | 0.82 | ADRB1 (0.57) | ADRB1HTR2CHTR6HTR2BHTR2A | |
| SCHEMBL23777738 | 0.82 | ADRB1 (0.57) | ADRB1HTR2CHTR6HTR2BHTR2A | |
| SCHEMBL335553 | 0.82 | ADRB1 (0.57) | ADRB1HTR2CHTR6HTR2BHTR2A | |
| SCHEMBL21098946 | 0.82 | ADRB1 (0.55) | ADRB1HTR2CHTR6HTR2BHTR2A | |
| SCHEMBL21098945 | 0.82 | ADRB1 (0.55) | ADRB1HTR2CHTR6HTR2BHTR2A | |
| SCHEMBL21098426 | 0.81 | ADRB1 (0.54) | ADRB1HTR2CHTR6HTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174270-B2 | Crystal form of 3,4-dihydrothieno[3,2-d]pyrimidine compound and preparation method thereof | PHAENO THERAPEUTICS CO., LTD. (CN) | 2021-11-16 | — | — | US | disclosed |
| EP-3498715-B1 | ANTI-HCMV VIRUS COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2021-06-09 | — | — | EP | disclosed |
| US-20210024538-A1 | Crystal Form of 3,4-Dihydrothieno[3,2-D]Pyrimidine Compound and Preparation Method Thereof | PHAENO THERAPEUTICS CO., LTD. (CN) | 2021-01-28 | — | — | US | disclosed |
| EP-3753942-A1 | CRYSTAL FORM OF 3,4-DIHYDROTHIENO[3,2-D]PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR | Medshine Discovery Inc. (CN) | 2020-12-23 | — | — | EP | disclosed |
| US-10851112-B2 | Anti-HCMV virus compound | MEDSHINE DISCOVERY INC. (CN) | 2020-12-01 | — | — | US | disclosed |
| WO-2019154192-A1 | CRYSTAL FORM OF 3,4-DIHYDROTHIENO[3,2-D]PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR | 南京明德新药研发股份有限公司 | 2019-08-15 | — | — | WO | disclosed |
| US-20190202838-A1 | ANTI-HCMV VIRUS COMPOUND | PHAENO THERAPEUTICS CO., LTD. (CN) | 2019-07-04 | — | — | US | disclosed |
| EP-3498715-A1 | ANTI-HCMV VIRUS COMPOUND | Medshine Discovery Inc. (CN) | 2019-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174270-B2 | Crystal form of 3,4-dihydrothieno[3,2-d]pyrimidine compound and preparation method thereof | TYMP, TPMT, HELZ | ADRB1 4455/4885HTR2C 1950/4885HTR6 1500/4885 |
| US-20190202838-A1 | ANTI-HCMV VIRUS COMPOUND | RPL35, RPL5, RPL17 | ADRB1 3842/4885HTR2C 4587/4885HTR6 2538/4885 |
| US-10851112-B2 | Anti-HCMV virus compound | RPL35, RPL5, RPL17 | ADRB1 3842/4885HTR2C 4587/4885HTR6 2538/4885 |
| US-20210024538-A1 | Crystal Form of 3,4-Dihydrothieno[3,2-D]Pyrimidine Compound and Preparation Method Thereof | TYMP, TPMT, HELZ | ADRB1 4455/4885HTR2C 1950/4885HTR6 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.